Our Research

Ovarian Hormone Withdrawal and Suicide Risk: An Experimental Approach

K99/R00-NIMH-109667

Experimentally delineating the causal role of perimenstrual withdrawal from estradiol, progesterone, and their combination in acute suicide risk.

Cyclical Neuroactive Steroid Changes, Arousal, and Proximal Suicide Risk: An Experimental Approach

R01-NIMH-120843

Experimentally delineating the neurosteroid pathways which may be involved in perimenstrual worsening of depression and suicide risk. 

Estrogen Effects on ADHD and Cognition

R01-NIMH-119119

Examining the potential role of estrogen fluctuations across the menstrual cycle in symptoms of attention deficit hyperactivity disorder (ADHD). 

Adolescent Girls’ Risk for Suicide Across the Menstrual Cycle: Examining Stress and Negative Valence Systems Longitudinally

R01-NIMH-122446

Examining the impact of the adolescent menstrual cycle on suicidal thoughts and behaviors.

Measuring Inflammatory Reactivity as a Mediator of Early Adversity’s Effects on Interpersonal Dysfunction in Women

Mind and Life Foundation

The purpose of this study is to examine, in the context of a randomized controlled trial of mindfulness-based stress reduction, the unique effects of mindfulness training on inflammatory responses to psychosocial stress among females with and without early life abuse. 

Using a Perimenstrual Steroid Stabilization Experiment to Validate a Smartphone-Based Assessment Protocol for Perimenstrual Mood Dysregulation and Suicidality

Gia Allemand Foundation

The purpose of this study is to pilot a smartphone-administered version of the Carolina Premenstrual Assessment Scoring System (C-PASS) diagnostic system for cyclical mood disorders in the context of the PI’s K99 award from NIMH. This project seeks to validate the steroid-sensitive nature of the C-PASS in the context of the K99 experimental design.