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Release Date: 05/20/2022 Source: TheScientist

Epigenome Editing Decreases Alcohol Seeking and Anxiety in Rats

More than 15 million people worldwide struggle with alcohol use disorder, a chronic relapsing condition that can have severe consequences on a person’s physical, emotional, and mental wellbeing. Despite its prevalence, few effective medications to treat alcohol addiction exist, and the risk of relapse after seeking treatment can be up to 90 percent within four years.

Release Date: 05/17/2022 Source: Big Think

Gene editing could reverse anxiety and alcohol-use disorder

Exposure to alcohol during adolescence can leave a person vulnerable to a lifetime of psychiatric challenges, such as anxiety problems and alcohol-use disorder. Epigenetic modifications arise after adolescent alcohol use, which block the expression of proteins associated with higher-order cognitive and emotional processes during adulthood. CRISPR gene editing can reverse the disruptive epigenetic modification, and alleviate anxiety and alcoholism.

Release Date: 05/04/2022 Source: UIC Today

A ‘factory reset’ for the brain cures anxiety, drinking behavior

“Early binge drinking can have long-lasting and significant effects on the brain and the results of this study offer evidence that gene editing is a potential antidote to these effects, offering a kind of factory reset for the brain, if you will,” said study senior author Subhash Pandey, the Joseph A. Flaherty Endowed Professor of Psychiatry and director of the Center for Alcohol Research in Epigenetics at UIC. The study is issued by researchers from the University of Illinois Chicago who have been studying the effects of early life binge drinking on health later in life.

Release Date: 06/14/2021 Source: UIC Today

UIC research identifies potential pathways to treating alcohol use disorder,…

A discovery from researchers at the University of Illinois Chicago may lead to new treatments for individuals who suffer from alcohol use disorder and depression. 

Release Date: 12/11/2020

Congratulations to our own, Dr. Subhash Pandey, who is now the Joseph A.…

Subhash Pandey, PhD Joseph A. Flaherty Professor of Psychiatry The 2020-21 University Scholar, University of Illinois 

Release Date: 11/04/2020 Source: UIC Today

University Scholar Subhash Pandey

The University Scholars Program, now in its 35th year, honors faculty members for superior research and teaching, along with great promise for future achievements. The award provides $15,000 a year for three years.