1. Profile
  2. Natania Crane

Natania Crane PhD

Natania Crane
  • Assistant Professor
  • Associate Director of the UIC Recovery Clinic
  • Department of Psychiatry, UIC
Contact Information
  • ncrane3 [at]
  • (312) 413-4453
  • School of Public Health / Psychiatric Institute (SPHPI)
    1601 W. Taylor St.
    SPHPI MC 912
    Chicago IL 60612
  • Room #:450

Dr. Crane is an Assistant Professor of Psychiatry and the Associate Director of the UIC Recovery Clinic. She is a Licensed Clinical Psychologist. Her research utilizes multiple methods (i.e., fMRI, EEG, cognitive, clinical, and self-report measures) to examine the brain and behavioral risk factors and consequences of Substance Use Disorders, especially Cannabis Use Disorder. An important aspect of her research is studying the relationship between clinical mental health factors and substance use, particularly between depression and cannabis use. Dr. Crane received her PhD in Clinical Psychology, completed her Clinical Internship and T32 Postdoctoral Fellowship at UIC, with an emphasis in Neuropsychology. She has received Early Career Travel Awards from the American College of Neuropsychopharmacology, the Society of Biological Psychiatry, the National Institute on Drug Abuse, and the American Psychological Foundation, as well as a K23 Early Career Development Award from the National Institute on Drug Abuse.

  • Brain and behavioral risk factors for Substance Use Disorders, cannabis, cannabinoids, alcohol, nicotine, mood disorders, sex/gender differences, neuropsychology

  • Selected Publications

    Denson, R.K., Brooks, J.M., Pinna, G., & Crane, N.A. (2023). Effects of Cannabidiol in Adolescent Depression and Anxiety Disorders: A Systematic Review of Clinical and Preclinical Research. Adolescent Psychiatry, 2210-6774.

    Crane, N.A. & Wade, N.E. (2023). Cannabis and Neuropsychology. In G. G. Brown, T. Z. King, K. Y. Haaland, & B. Crosson (Eds.), APA Handbook of Neuropsychology: Vol. 1. Neurobehavioral Disorders and Conditions: Accepted Science and Open Questions. American Psychological Association. 

    * Crane, N.A., Langenecker, S.A., & Mermelstein, R.J. (2021). Risk Factors for Alcohol, Marijuana, and Cigarette Polysubstance Use During Adolescence and Young Adulthood: A 7-Year Longitudinal Study of Youth at High Risk for Smoking Escalation. Addictive Behaviors, 119: 106944. PMID: 33872847. 

    * Crane, N.A. & Phan, K.L. (2021). Effect of Δ9-Tetrahydrocannabinol on Frontostriatal Resting State Functional Connectivity and Subjective Euphoric Response in Healthy Young Adults. Drug and Alcohol Dependence, 221: 108565. PMID: 33592558. 

    * Crane, N.A., Chang, F., Kinney, K.L., & Klumpp, H. (2021). Individual Differences in Striatal and Amygdala Response to Emotional Faces are Related to Symptom Severity in Social Anxiety Disorder. Neuroimage: Clinical, 30: 102615. PMID: 33735785. 

    * Crane, N.A., Funkhouser, C.J., Burkhouse, K.L., Klumpp, H., Phan, K.L., & Shankman, S.A. (2021). Cannabis Users Demonstrate Enhanced Neural Reactivity to Reward: An Event-Related Potential and Time-Frequency EEG Study. Addictive Behaviors, 113: 106669. PMID: 33035810. 

    * Radoman, M., Crane, N.A., Gorka, S.M., Weafer, J., Langenecker, S.A., de Wit, H., & Phan, K.L. (2021). Striatal Activation to Monetary Reward is Associated with Alcohol Reward Sensitivity. Neuropsychopharmcology, 46(2): 343-350. PMID: 32505126. 

    * Langenecker, S.A., Kling, L.R., Crane, N.A., Gorka, S.M., Nusslock, R., Damme, K.S., Weafer, J., de Wit, H., & Phan, K.L. (2020). Anticipation of Monetary Reward in Amygdala, Insula, Caudate are Predictors of Pleasure Sensitivity to d-Amphetamine Administration. Drug and Alcohol Dependence, 206: 107725. PMID: 31757518. 

    * Crane, N.A., Verges, A., Kamali, M., Bhaumik, R., Ryan, K.A., Marshall, D.F., Saunders, E.F., Kassel, M.T., Weldon, A.L., McInnis, M.G., & Langenecker, S.A. (2020). Developing Dimensional, Pandiagnostic Inhibitory Control Constructs with Self-Report and Neuropsychological Data. Assessment, 27: 787-802. PMID: 29405754. 

    * Weafer, J., Crane, N.A., Gorka, S.M., Phan, K.L., & de Wit, H. (2019). Neural Correlates of Inhibition and Reward Are Negatively Associated. Neuroimage, 196: 188-194. PMID: 30974242. 
    * Crane, N.A., Gorka, S.M., Weafer, J., Langenecker, S.A., de Wit, H., & Phan, K.L. (2018). Neural Activation to Reward is Associated with Amphetamine Reward Sensitivity. Neuropsychopharmacology, 43(8): 1738-1744. PMID: 29581536. 

    * Crane, N.A., Gorka, S.M., Phan, K.L., & Childs, E. (2018). Amygdala-Orbitofrontal Functional Connectivity Mediates the Relationship between Sensation Seeking and Alcohol Use among Binge-drinking Adults. Drug and Alcohol Dependence, 192: 208-214. PMID: 30268936. 

    * Crane, N.A., Gorka, S.M., Burkhouse, K.L., Afshar, K., Greenstein, J.E., Aase, D.M., Proescher, E., Schroth, C., Kennedy, A.E., & Phan, K.L. (2018). Neural response to errors is associated with problematic alcohol use over time in combat-exposed returning veterans: An event-related potential study. Drug and Alcohol Dependence, 183: 155-161. PMID: 29253797. 

    * Crane, N.A., Gorka, S.M., Weafer, J., Langeneker, S.A., de Wit, H., & Phan, K.L. (2017). Preliminary Evidence for Disrupted Nucleus Accumbens Reactivity and Connectivity to Reward in Binge Drinkers. Alcohol and Alcoholism, 52(6): 647-654. PMID: 29016710. 

    * Crane, N.A., Jenkins, L.M., Bhaumik, R., Dion, C., Gowins, J.R., Mickey, B.J., Zubieta, J.K., & Langenecker, S.A. (2017). Multidimensional Prediction of Treatment Response to Antidepressants with Cognitive Control and fMRI. Brain, 140(2): 472-486. PMID: 28122876. 
    * Crane, N.A., Schuster, R.M., Fusar-Poli, P., & Gonzalez, R. (2013). Effects of cannabis on neurocognitive functioning: recent advances, neurodevelopmental influences, and sex differences. Neuropsychology Review, 23(2): 117-137. PMID: 23129391. 

    * Crean, R.D., Crane, N.A., & Mason, B.J. (2011). An evidence-based review of acute and long-term effects of cannabis use on executive cognitive functions. Journal of Addiction Medicine, 5(1): 1-8. PMID: 21321675.

Title Description Investigator(s) Category Status
Brain-Behavior Markers of Reward and Cannabis Abuse Risk In Young Adults K23DA048132 REWARD Lab On-going
Context, Subjective and Cognitive Experiences with Patterns of Tobacco and Cannabis Co-Use in Young Adults R01DA051157  The objective of this study is to examine, in real time, the proximal antecedents and consequences of tobacco and cannabis co-use in young adults using Ecological Momentary Assessment (EMA). REWARD Lab On-going

*System-generated list from psychiatry research website.