1. Profile
  2. Mark Rasenick

Mark Rasenick PhD

Mark Rasenick
  • Distinguished Professor of Physiology & Biophysics and Psychiatry
  • Director, Biomedical Neuroscience Training Program
  • Research Career Scientist, Jesse Brown VAMC
  • University of Illinois Chicago College of Medicine
Contact Information
  • raz [at]
  • 312-996-6641
  • Institute for Juvenile Research (IJR)
    1747 W. Roosevelt Rd.
    Chicago IL 60612

Dr. Rasenick’s work has focused on G protein signaling in the nervous system and the relationship of neurotransmitter activation to rapid modification of the cytoskeleton.  He has been particularly interested in how G proteins and the cytoskeleton work in concert to modify synaptic shape and to form a molecular basis for depression and the action of antidepressant drugs.  The most recent work from his group suggests the possibility of a simple blood test indicating depression and therapeutic response to antidepressant therapy. This has led to the creation of Pax Neuroscience, which recently received SBIR funding from NIMH. Dr. Rasenick’s research continues to be funded by the NIH, the Veterans Administration, as well as by other government, philanthropic and industry sources.  He is principal investigator of an NIMH training grant, “Training in the Neuroscience of Mental Health”, which supports graduate students and postdoctoral fellows in the neurosciences.  He is also the co-founder of UIC’s Graduate Program in Neuroscience.  He has served on many scientific review panels (NIH, NSF, DOD), and editorial boards and is the author of numerous publications.  Dr. Rasenick has received honors both for teaching and research, including the Searle Young Faculty Award from the Chicago Community Trust, the University Scholar Award and Distinguished Faculty Award from the University of Illinois, a Research Scientist Award from the NIMH, and a Robert Wood Johnson Health Policy Fellowship from the Institute of Medicine/National Academy of Sciences.  He is an elected fellow of the American College of Neuropsychopharmacology and the American Association for the Advancement of Science and an elected member of the Dana Alliance for Brain Research and the Cuban Academy of Science.

In addition to research and teaching, Dr. Rasenick is active in public policy.  He is a member of the Board of Directors of the American Brain Coalition and the National Association for Biomedical Research.  He served as a member of the Commission on Social Action of Reform Judaism and the Chapters committee, Government and Public Affairs Committee and International Affairs Committee of the Society for Neuroscience.  He also serves or has served on the Public Affairs/Outreach committees of the American Society for Biochemistry and Molecular Biology and the American College of Neuropsychopharmacology, and chaired that Committee for ACNP. He currently chairs the Advocacy Committees for the American Brain Coalition and for the National Network of Depression Centers.  He was a member of the Basic and Clinical Neuroscience Links Committee for the International Brain Research Organization (IBRO) and was appointed a Global Health Research Ambassador by the Paul Rogers Society—Research!America.  While a Robert Wood Johnson Fellow (1999-2000), he was a staff member of the Senate Committee on Health, Education, Labor, and Pensions with the late Senator Edward M. Kennedy, (D Mass.).  During this time, he worked on legislation concerning Cancer screening, Medicare Prescription Drugs, Organ Transplantation Policy and Mental Health Policy.  He is also involved in international outreach for neuroscience and has organized programs designed to foster international cooperation in the basic and clinical neurosciences in Vietnam, Cuba and throughout Latin America.  He has testified before the Senate Committee on Foreign Relations concerning outreach to Cuban biomedical scientists. 

  • academic
Date Released Title Source
12/15/2023 Dr. Mark Rasenick is installed as president of the American Brain Coalition and was also quoted in a Wired Magazine article "Why does it take so long for antidepressants to work--a possible solution" Wired Magazine
12/15/2023 Dr. Mark Rasenick presented lectures in 3 locations (Harvard, Tunis and Quebec)
07/07/2023 Dr. Mark Rasenick presented a symposium on confluence and contrast between the antidepressant properties ketamine and psychedelics International Society for Serotonin Research
03/28/2023 A prize has also been awarded to Dr. Mark Rasenick, University of Illinois, Chicago, USA for his work on the importance of lipid rafts for signal transduction mediated by antidepressants and ketamine.
08/24/2022 Dr. Mark Rasenick was invited to give the presentations this summer
04/20/2022 Dr. Sally Weinstein was interviewed on NBC5 Evening News, along with Dr. Mark Rasenick, to discuss the impact of Dr. Rasenick’s breakthrough depression research in the field NBC 5 Chicago
04/20/2022 UIC researchers develop biomarker to detect depression Fox 32 Chicago
07/23/2019 Were U.S. Diplomats Attacked in Cuba? Brain Study Deepens Mystery The New York Times
03/11/2019 FDA Approves Ketamine Nasal Spray as New Depression Treatment WTTW
02/23/2019 Dr. Rasenick becomes a member of the National Academy of Science of Cuba UI Center on Depression & Resilience
The Anna-Monika-Foundation is proud to announce the prize winners of the 28th Anna-Monika Prize for Depression Research