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  2. Mark M. Rasenick

Mark M. Rasenick PhD

Mark M. Rasenick
Designation
  • Distinguished Professor of Physiology & Biophysics and Psychiatry
  • Director, Biomedical Neuroscience Training Program
  • Research Career Scientist, Jesse Brown VAMC
  • University of Illinois Chicago College of Medicine
Gender Pronouns
  • he/him
Contact Information
  • raz [at] uic.edu
  • (312) 996-6641
  • Institute for Juvenile Research (IJR)
    1747 W. Roosevelt Rd.
    Chicago IL 60612
  • Room #:2095 COMRB

Mark Rasenick is currently Distinguished UIC Professor of Physiology & Biophysics, and Psychiatry, and Director of the Biomedical Neuroscience Training Program at the University of Illinois College of Medicine and a Research Career Scientist at the Jesse Brown VAMC.

Dr. Rasenick’s work has focused on G protein signaling in the nervous system and the relationship of neurotransmitter activation to rapid modification of the cytoskeleton.  He has been particularly interested in how G proteins and the cytoskeleton work in concert to modify synaptic shape and to form a molecular basis for the action of antidepressant drugs and, perhaps, the etiology of depression.  Dr. Rasenick has been funded (continuously since 1984) by the NIH.  He has also been funded by other federal agencies (VA, NIA, NSF, DOD) and by industry sources.  He has served on many scientific review panels (NIH, NSF, DOD), provided extensive editorial activities and is the author of numerous publications.  Dr. Rasenick has received honors both for teaching and research, including the Searle Young Faculty Award from the Chicago Community Trust, the University Scholar Award and Distinguished Faculty Award from the University of Illinois, a Research Scientist Award from the NIMH, and a Robert Wood Johnson Health Policy Fellowship from the Institute of Medicine/National Academy of Sciences.  Dr. Rasenick is a Fellow of the American College of Neuropsychopharmacology and he received the 2023 Anna Monika prize for depression research. Additionally, he was elected a member of the National Academy of Science of Cuba.

In addition to research and teaching, Dr. Rasenick is active in public policy.  He is currently chair of the American Brain Coalition.  While a Robert Wood Johnson Fellow (1999-2000), he was a staff member of the Senate Committee on Health, Education, Labor, and Pensions with Senator Edward M. Kennedy, (D Mass.).  He is also involved in international outreach for neuroscience and has organized programs designed to foster international cooperation in the basic and clinical neurosciences in Vietnam, Cuba and throughout Latin America.  In 1970, he was a member of the People’s Peace Treaty delegation to Hanoi and, more recently, has worked on reconciliation projects in Southeast Asia.

  • academic

    Neurobiology of Depression.  G protein signaling and the cytoskeleton.  Influence of membrane microdomains on GPCR signaling and antidepressant action.  Biomarkers for depression.

     

  • personal

    Sailing, cycling and weight training.

  • Project Name 1 Biomarkers for depression and to predict antidepressant response

  • Project Name 2 The role of the cytoskeleton in cAMP signaling

Date Released Title Source
09/09/2025 The American Brain Coalition has held two recent Congressional Briefings (March and June)
09/09/2025 Drs. Ajilore, Leow, Rasenick and colleagues published an article in Molecular Psychiatry Molecular Psychiatry
02/25/2025 Dr. Mark Rasenick was invited to present at the Anna Monika Foundation, Compass Pathways and BioHabana 24
12/15/2023 Dr. Mark Rasenick presented lectures in 3 locations (Harvard, Tunis and Quebec)
12/15/2023 Dr. Mark Rasenick is installed as president of the American Brain Coalition and was also quoted in a Wired Magazine article "Why does it take so long for antidepressants to work--a possible solution" Wired Magazine
07/07/2023 Dr. Mark Rasenick presented a symposium on confluence and contrast between the antidepressant properties ketamine and psychedelics International Society for Serotonin Research
03/28/2023 A prize has also been awarded to Dr. Mark Rasenick, University of Illinois, Chicago, USA for his work on the importance of lipid rafts for signal transduction mediated by antidepressants and ketamine.
08/24/2022 Dr. Mark Rasenick was invited to give the presentations this summer
04/20/2022 Dr. Sally Weinstein was interviewed on NBC5 Evening News, along with Dr. Mark Rasenick, to discuss the impact of Dr. Rasenick’s breakthrough depression research in the field NBC 5 Chicago
04/20/2022 UIC researchers develop biomarker to detect depression Fox 32 Chicago
07/23/2019 Were U.S. Diplomats Attacked in Cuba? Brain Study Deepens Mystery The New York Times
03/11/2019 FDA Approves Ketamine Nasal Spray as New Depression Treatment WTTW
02/23/2019 Dr. Rasenick becomes a member of the National Academy of Science of Cuba UI Center on Depression & Resilience
The Anna-Monika-Foundation is proud to announce the prize winners of the 28th Anna-Monika Prize for Depression Research