2. Profile
  3. Jonathan P. Stange

Jonathan P. Stange PhD

Jonathan P. Stange
Designation
  • Assistant Professor of Psychology, University of Southern California
  • T32 Postdoctoral Fellow in Neuroimaging, University of Illinois Chicago, 2016-2017
Website

Dr. Stange’s research focuses on identifying mechanisms and outcomes of inflexible cognitive and affective processes in mood disorders. His current work seeks to identify how disrupted interactions between cognitive and affective processes may underlie maladaptive affect regulation in individuals at risk for problems such as depression and suicide.  This work involves the use of neuroimaging, autonomic psychophysiology, and experimental, behavioral, and longitudinal methods. Increasingly, this work involves studying affect regulation outside of the lab in “real-world” contexts that may have greater ecological validity than traditional laboratory-based methods, by using ambulatory assessment techniques (e.g., ambulatory autonomic psychophysiology, sleep actigraphy, and behavior with ecological momentary assessment). By improving our understanding of how risk factors may vary between individuals, and within individuals across contexts over time, these studies will have implications for the development of real-time, person-centered metrics for detecting periods of risk, and for intervening to improve affect regulation and reduce risk.

This work has been funded by the National Institute of Mental Health as a K23 Career Development Award and an F31 National Research Service Award, and by grants from the Brain and Behavior Research Foundation (NARSAD Young Investigator Award), the Portes Foundation and Institute of Medicine of Chicago, the Association for Psychological Science, the American Psychological Foundation, and the American Psychological Association.

Dr. Stange received a Ph.D. in clinical psychology from Temple University. He completed his clinical internship and NIMH T32 postdoctoral fellowship in neuroimaging at UIC.

  • psychiatry
    • Neural mechanisms of the cognitive control of negative affect
    • Person-centered (repeated-measure, within-subject) metrics of cognitive-affective risk processes
    • Ambulatory assessment of affect regulation in real-world contexts (e.g., wearables for measuring within-subject variability in psychophysiology, behavior, and affect)
    • Interactions between cognitive and affective systems across the development of mood disorders
    • Longitudinal multi-level assessment of cognitive and affective processes in mood disorders
    • Cognitive vulnerability-stress models of mood disorders
  • From Networks to the Real World: Integrating Neural and Autonomic Processes of Loss (NIMH K23)
  • Probing Autonomic and Network Mechanisms of Emotion Regulation in Major Depressive Disorder (NARSAD Young Investigator Award)
  • Identifying Mechanisms of Proximal Suicide Risk Using Ambulatory Assessment (Portes Foundation and Institute of Medicine of Chicago)
https://www.ncbi.nlm.nih.gov/pubmed?term=stange%20jp%5BAuthor%5D

  • Stange, J. P., Jenkins, L. M., Pocius, S., Kreutzer, K., Bessette, K., DelDonno, S. R., Kling, L. R., Bhaumik, R., Welsh, R. C., Keilp, J. G., Phan, K. L., & Langenecker, S. A. (in press). Using resting-state intrinsic network connectivity to identify suicide risk in mood disorders. Psychological Medicine.

    Stange, J. P., Kleiman, E. M., Mermelstein, R. J., & Trull, T. J. (in press). Using ambulatory assessment to measure dynamic risk processes in affective disorders. Journal of Affective Disorders.

    Stange, J. P., MacNamara, A., Kennedy, A. E., Hajcak, G., Phan, K. L., & Klumpp, H. (in press). Brain-behavioral adaptability predicts response to cognitive behavioral therapy for emotional disorders: A person-centered event-related potential study. Neuropsychologia.

    Langenecker, S. A., Klumpp, H., Peters, A. T., Crane, N .A., DelDonno, S. R., Bessette, K. L., Ajilore, O., Leow, A., Shankman, S., Phan, K. L., Zubieta, J-K., Mickey, B. J., & Stange, J. P. (2019). Multidimensional imaging techniques for prediction of treatment response in mood disorders. Progress in Neuro-Psychopharmacology & Biological Psychiatry, 21, 38-48.

    Burkhouse, K. L., Stange, J. P., Jacobs, R. H., Bhaumic, R., Bessette, K. L., Peters, A. T., Crane, N. A., Kreutzer, K. A., Fitzgerald, K., Monk, C., Welsh, R. C., Phan, K. L., & Langenecker, S. A. (2019). Developmental changes in resting-state functional networks in individuals with and without internalizing psychopathologies. Depression and Anxiety, 36(2), 141-152.

    Peters, A. T., Jenkins, L. M., Stange, J. P., Bessette, K. L., Skerrett, K. A., Kling, L. R., Welsh, R., Milad, M., Phan, K. L., & Langenecker, S. A. (2019). Pre-scan cortisol is differentially associated with enhanced cross-network connectivity to the cognitive control network in young adults with a history of depression. Psychoneuroendocrinology, 104, 219-227.

    Stange, J. P., Zulueta, J., Langenecker, S. A., Ryan, K. A., Piscitello, A., Duffecy, J., McInnis, M. G., Nelson, P., Ajilore, O., & Leow, A. (2018). Let your fingers do the talking: Passive typing instability predicts future mood outcomes. Bipolar Disorders, 20(3), 285-288.

    Stange, J. P., Jenkins, L. M., Hamlat, E. J., Bessette, K. L., DelDonno, S., Kling, L. R., Passarotti, A. M., Phan, K. L., Klumpp, H., Ryan, K. A., & Langenecker, S. A. (2018). Disrupted engagement of networks supporting hot and cold cognition in remitted major depressive disorder. Journal of Affective Disorders, 227, 183-191.

    Stange, J. P., Jenkins, L. M., Bessette, K. L., Kling, L. R., Bark, J. S., Shepard, R., Hamlat, E. J., DelDonno, S., Phan, K. L., Passarotti, A. M., Ajilore, O., & Langenecker, S. A. (2018). Predictors of attrition in longitudinal neuroimaging research: Inhibitory control, head movement, and resting-state functional connectivity. Brain Connectivity, 8(9), 527-536.

    Quinn, M. E., Stange, J. P., Jenkins, L. M., Corwin, S., DelDonno, S. R., Bessette, K. L., Welsh, R. C., & Langenecker, S. A. (2018). Cognitive control impairment and resting state networks disruption in remitted major depressive disorder: An early developmental correlate of childhood adversity. Social Cognitive Affective Neuroscience, 13(10),1081-1090.

    Stange, J. P., Bessette, K. L., Jenkins, L., Peters, A. T., Feldhaus, C., Crane, N. A., Ajilore, O., Jacobs, R. H, Watkins, E. R., & Langenecker, S. A. (2017). Attenuated intrinsic connectivity within cognitive control network among individuals with remitted depression: Temporal stability and association with negative cognitive styles. Human Brain Mapping, 38(6), 2939-2954.

    Stange, J. P., MacNamara, A., Barnas, O., Kennedy, A. E., Hajcak, G., Phan, K. L., & Klumpp, H. (2017). Neural markers of attention to aversive pictures predict response to cognitive behavioral therapy in anxiety and depression. Biological Psychology, 123, 269-277.

    Jenkins, L., Stange, J. P., Barba, A., DelDonno, S., Kling, L., Briceno, E., Weisenbach, S., Phan, K. L., Shankman, S., Welsh, R. C., & Langenecker, S. A. (2017). Integrated cross-network connectivity of amygdala, insula and subgenual cingulate associated with facial emotion perception in healthy controls and remitted major depressive disorder. Cognitive, Affective, and Behavioral Neuroscience, 17(6), 1242-1254.

    Stange, J. P., Hamilton, J. L., Olino, T. M., Fresco, D. M., & Alloy, L. B. (2017). Autonomic reactivity and vulnerability to depression: A multi-wave study. Emotion, 17(4), 602-615.

    Stange, J. P., Hamilton, J. L., Fresco, D. M., & Alloy, L. B. (2017). Flexible parasympathetic responses to sadness facilitate spontaneous affect regulation. Psychophysiology, 54(7), 1054-1069.

    Stange, J. P., Hamilton, J. L., Fresco, D. M., & Alloy, L. B. (2017). Perseverate or decenter? Differential effects of metacognition on the relationship between parasympathetic inflexibility and symptoms of depression in a multi-wave study. Behaviour Research and Therapy, 97, 123-133.

    Stange, J. P., Alloy, L. B., & Fresco, D. M. (2017). Inflexibility and vulnerability to depression: A systematic qualitative review. Clinical Psychology: Science and Practice, 24(3), 245-276.

    Stange, J. P., Connolly, S. L., Burke, T. A., Hamilton, J. L., Hamlat, E. J., Abramson, L. Y., & Alloy, L. B. (2016). Inflexible cognition predicts first onset of major depression in adolescence. Depression and Anxiety, 33(11), 1005-1012.

    Stange, J. P., Sylvia, L. G., Magalhães, P. V., Miklowitz, D. J., Otto, M. W., Frank, E., Yim, C., Berk, M., Dougherty, D. D., Nierenberg, A. A., & Deckersbach, T. (2016). Affective instability and the course of bipolar depression: Results from the STEP-BD randomized, controlled trial of psychosocial treatment.  British Journal of Psychiatry, 208(4), 352-358.

    Stange, J. P., Sylvia, L. G., Magalhães, P. V., Miklowitz, D. J., Otto, M. W., Frank, E., Berk, M., Hansen, N. S., Dougherty, D. D., Nierenberg, A. A., & Deckersbach, T. (2014). Extreme attributions predict suicidal ideation and suicide attempts in bipolar disorder: Prospective data from STEP-BD. World Psychiatry, 13(1), 95-96.

    Stange, J. P., Sylvia, L. G., Magalhães, P. V., Miklowitz, D. J., Otto, M. W., Frank, E., Berk, M., Nierenberg, A. A., & Deckersbach, T. (2013). Extreme attributions predict the course of bipolar depression: Results from the STEP-BD randomized controlled trial of psychosocial treatment.  Journal of Clinical Psychiatry, 74(3), 249-255.