1. Profile
  2. Edwin H. Cook Jr.

Edwin H. Cook Jr. MD

Edwin H. Cook Jr.
  • Earl M Bane Professor of Psychiatry
  • Associate Head, Clinical Services
  • Director, Program for Neurodevelopmental Disorders
Contact Information
  • edcook [at]
  • (312) 413-4537
  • Institute for Juvenile Research (IJR)
    1747 W. Roosevelt Rd.
    Chicago IL 60612

Dr. Cook is the Director of Program for Neurodevelopmental Disorders and the Associate Head of Clinical Services in the department. Dr. Cook is board certified in both Psychiatry and Child and Adolescent Psychiatry. He specializes in treating comorbid psychiatric disorders for individuals with autism spectrum disorder. Dr. Cook is also the Earl M. Bane Professor of Psychiatry.

  • psychiatry

    Neurodevelopmental disorders, Genetic research on child onset neuropsychiatric disorders.

  • Cook, E.H.: Autism: Review of neurochemical investigation. Synapse 1990,6:292 308.

    Cook, E.H., Lindgren, V., Leventhal, B.L., Courchesne, R., Lincoln, A., Shulman, C., Lord, C., Courchesne, E.: Autism or atypical autism in maternally but not paternally derived proximal 15q duplication. American Journal of Human Genetics 1997,60:928-934.

    Cook, Jr., E.H., Scherer, S.W.: Copy-number variations associated with neuropsychiatric conditions. Nature, 2008,455:919-923.

    Kumar, R.A., Karamohamed, S., Sudi, J., Conrad, D.F., Brune, C., Badner, J.A., Gilliam, T.C., Nowak, N.J., Cook E.H., Dobyns, W.B., Christian, S.L.: Recurrent 16p11.2 microdeletions in autism. Human Molecular Genetics 2008,17:628-638.

    Wakschlag, L.S., Kistner, E.O., Pine, D.S., Biesecker, G., Pickett, K.E., Skol, A., Dukic, V., Blair, R.J., Leventhal, B.L., Cox, N., Burns, J., Kasza, K.E., Wright, R.J., Cook, E.H.: Interaction of prenatal exposure to cigarettes and MAOA genotype in pathways to youth antisocial behavior. Molecular Psychiatry, 2010,15:928-937. PMC2905677.

    Kistner-Griffin, E., Brune, C.W., Davis, L.K., Sutcliffe, J.S., Cox, N.J., Cook, E.H.: Parent-of-origin effects of the serotonin transporter gene associated with autism. American Journal of Medical Genetics (Neuropsychiatric Genetics), 2011,156:139-144. PMC3438509.

    Sanders, S.J., Ercan-Sencice, A.G., Hus, V., Luo, R., Murtha, M.T., Moreno-De-Luca, S., Chu, S.H., Moreau, M.P., Gupta, A.R., Thomson, S.A., Mason, C.E., Bilguvar, K., Celestino-Soper, P.B.S., Choi, M., Crawford, E.L., Davis, L., Davis Wright, N.R., Dhodapkar, R.M., DiCola, M., DiLullo, N.M., Fernandez, T.V., Fielding-Singh, V., Fishman, D.O., Frahm, S., Garagaloyan, R., Goh, G.S., Kammela, S., Klei, L., Lowe, J.K., Lund, S.C., McGrew, A.D., Meyer, K.A., Moffat, W.J., Murdoch, J.D., O'Roak, B.J., Ober, G.T., Pottenger, R.S., Raubeson, M.J., Song, Y., Wang, Q., Yaspan, B.L., Yu, T.W., Yurkiewicz, I.R., Beaudet, A.L., Cantor, R.M., Curland, M., Grice, D.E., Günel, M., Lifton, R.P., Mane, S.M., Martin, D.M., Shaw, C.A., Sheldon, M., Tischfield, J.A., Walsh, C.A., Morrow, E.M., Ledbetter, D.H., Fombonne, E., Lord, C., Martin, C.L., Brooks, A.I., Sutcliffe, J.S., Cook, Jr., E.H., Geschwind, D., Roeder, K., Devlin, B., State, M.W.: Multiple recurrent de novo copy number variations (CNVs), including duplications of the 7q11.23 Williams-Beuren syndrome region, are strongly associated with autism. Neuron, 2011,70: 863-885.

    Hammock, E., Veenstra-VanderWeele, J., Yan, Z., Kerr, T.M., Morris, M., Anderson, G.M., Carter, C.S., Cook, E.H., Jacob, S.: Examining autism spectrum disorders by biomarkers: example from the oxytocin and serotonin systems. Journal of the American Academy of Child and Adolescent Psychiatry, 2012,51:712-721. PMC3672055.

    Neale, B.M., Kou, Y., Liu, L., Ma’ayan, A., Samocha, K.E., Sabo, A., Lin, C-F., Stevens, C., Wang, L-S., Makarov, V., Polak, P., Yoon, S., Maguire, J., Crawford, E.L., Campbell, N.G., Geller, E.T., Valladares, O., Shafer, C., Liu, H., Zhao, T., Cai, G., Lihm, J., Dannenfelser, R., Jabado, O., Peralta, Z., Nagaswamy, U., Reid, J.G., Newsham, I., Wu, Y., Lewis, L., Han, Y., Muzny, D., Voight, B.F., Lim, E., Rossin, E., Kirby, A., Flannick, J., Fromer, M., Shakir, K., Fennell, T., Garimella, K., Boyko, C., Gabriel, S., dePristo, M., Wimbish, J.R., Boone, B.E., Levy, S.E., Betancur, C., Sunyaev, S., Boerwinkle, E., Buxbaum, J.D., Cook, E.H., Devlin, B., Gibbs, R., Roeder, K., Schellenberg, G.D., Sutcliffe, J.S., Daly, M.J.: Patterns and rates of exonic de novo mutations in autism spectrum disorders. Nature, 2012,485:242-245. PMC3613847.

    D'Cruz, A.M., Ragozzino, M.E., Mosconi, M.W., Shrestha, S., Cook, E.H., Sweeney, J.A.: Reduced behavioral flexibility in autism spectrum disorders. Neuropsychology 2013,27:152-160. PMC3740947.

Title Description Investigator(s) Category Status
Laboratory of Developmental Neuroscience The Laboratory of Developmental Neuroscience is dedicated to studying the developmental neurobiological basis of pediatric onset neuropsychiatric disorders. We use neurochemical and molecular genetic research tools to develop new knowledge that may lead to improvement in clinical pharmacology. Program for Neurodevelopmental Disorders On-going
Samples and Phenotype Committee Leadership in the Autism Sequencing Consortium Along with Catalina Betancur (France) and Louise Gallagher (Ireland), the Samples and Phenotypes Committee works with the larger Autism Sequencing Consortium to identify new genetic variants in autism spectrum disorder and to understand the relationship of genetic variation in ASD to phenotype. Program for Neurodevelopmental Disorders On-going

*System-generated list from psychiatry research website.