1. Profile
  2. Dale L. Smith

Dale L. Smith PhD

Dale L. Smith
  • Senior Data Scientist
Gender Pronouns
  • he/him
Contact Information
  • dlsmith8 [at]
  • (312) 996-8255
  • Institute for Juvenile Research (IJR)
    1747 W. Roosevelt Rd.
    Chicago IL 60612
  • Room #:254

Dr. Smith is a senior data scientist in the Psychiatry department’s Institute for Juvenile Research and Digital Mental Health program. His research focuses on statistical and machine learning applications in mental health and public health. This has included extensive collaborations in studies involving post-traumatic stress disorder, autism spectrum disorder, substance use disorders, and psychiatric outcomes in homeless youth and children with sleep disordered breathing. 

Prior to joining the psychiatry department at UIC, he served as a professor of psychology and statistics at the undergraduate and graduate levels for 15 years. He is an accredited professional statistician (PStat) with the American Statistical Association.

  • Statistical and machine learning applications in mental and public health, longitudinal data analysis, cognitive functioning in at-risk populations, sleep and mental health, juvenile mental health.

  • PTSD Treatment Outcomes

    Through collaboration with researchers at Rush University Medical Center, we examine factors related to treatment response and long-term outcomes among individuals undergoing PTSD treatment.

  • Project Name 2 Mobile Technologies to Support Youth Experiencing Homelessness

    Through collaboration with researchers at the University of California, Irvine, we are exploring smartphone and mobile technology interventions to support youth experiencing homelessness.

  • Data Science Approaches to Screening for Substance Use

    We are working to develop data science-driven algorithms to assist in identifying individuals with substance use disorders.

  • *Thompson HM, Sharma B, Smith DL, Bhalla S, Erondu I, Hazra A, Ilyas Y, Pachwicewicz P, Sheth NK, Chhabra N, Karnik NS, Afshar M. Machine Learning Techniques to Explore Clinical Presentations of COVID-19 Severity and to Test the Association With Unhealthy Opioid Use: Retrospective Cross-sectional Cohort Study. JMIR Public Health Surveill. 2022 Dec 8;8(12):e38158. doi: 10.2196/38158. PMID: 36265163; PMCID: PMC9746674.

    Held, P., Kaysen, D., & Smith, D. L. (2022, in press). Evaluating Changes in Negative Posttrauma Cognition as a Mechanism of PTSD Severity Changes in Two Separate Intensive Treatment Programs for Veterans. BMC Psychiatry.

    Smith, D. L., Kovacevic, M., Montes, M., Pridgen, S., & Held, P. (2022). Improving mental, physical, and social functioning through participation in a 3-week cognitive processing therapy-based intensive PTSD treatment. Journal of Anxiety Disorders, 88, 102560.

    Thompson, H. M., Sharma, B., Smith, D.L., Bhalla, S., Erondu, I., Hazra, A., Ilyas, Y., Pachwicewicz, P., Sheth, N.K., Chhabra, N., Karnik, N.S., & Afshar M. (2022, in press). Machine learning techniques to explore clinical presentation of COVID-19 disease severity and to test the association with unhealthy opioid use (UOU): Retrospective cross-sectional cohort study. JMIR Public Health and Surveillance.

    Smith, D.L. & Held, P. (2022, in press). Moving Toward Precision PTSD Treatment: Predicting Veterans’ Intensive PTSD Treatment Response Using Continuously Updating Machine Learning Models. Psychological Medicine.

    Splaine, C., Smith, D.L., & Held, P. (2022, in press). The role of time since trauma on treatment outcomes of veterans in two intensive posttraumatic stress disorder treatment programs. Journal of Traumatic Stress.

    Chhabra, N., Smith, D.L., Maloney, C.M., Archer, J., Sharma, B., Thompson, H.M., Afshar, M., & Karnik, N.S. (2022). The Identification of Subphenotypes and Associations with Health Outcomes in Patients with Opioid-Related Emergency Department Encounters Using Latent Class Analysis. International Journal of Environmental Research and Public Health, 19(4), 8882.

    Held, P., Schubert, R. A., Pridgen, S., Kovacevic, M., Montes, M., Christ, N. M., Banerjee, U, & Smith, D. L. (2022). Who will respond to intensive PTSD treatment? A machine learning approach to predicting response prior to starting treatment. Journal of psychiatric research, 151, 78-85.

    Held, P., Kovacevic, M., Petrey, K., Meade, E. A., Pridgen, S., Montes, M., Werner, B., Miller, M. L., Smith, D. L., Kaysen, D., & Karnik, N. S. (2022, in press). Treating PTSD at Home in a Single Week Using 1-Week Virtual Massed Cognitive Processing Therapy. Journal of Traumatic Stress.

    Meade, E.A., Smith, D.L., Montes, M., Norman, S.B., Held, P. (2022). Changes in guilt cognitions in intensive PTSD treatment among veterans who experienced military sexual trauma or combat trauma. Journal of Anxiety Disorders, 90, 102606.

    Held, P., Smith, D.L., Pridgen, S., Coleman, J.A., & Klassen, B.J. (2022, in press). More is not always better: 2 weeks of intensive cognitive processing therapy-based treatment are non-inferior to 3 weeks. Psychological Trauma: Theory, Research, Practice, and Policy.

    Held, P., Meade, E. A., Kovacevic, M., Smith, D. L., Pridgen, S., Coleman, J. A., & Klassen, B. J. (2022, in press). Building strong therapeutic relationships quickly: The effect of the perceived working alliance on veterans’ intensive PTSD treatment outcomes. Psychotherapy.

    Bhalla, S., Sharma, B., Smith, D. L., Boley, R., McCluskey, C., Ilyas, Y., Afshar, M., Balk, R., Karnik, N. S., & Keshavarzian, A. (2021). Unhealthy alcohol use is an independent risk factor for increased COVID-19 disease severity: observational cross-sectional study. JMIR Public Health and Surveillance, 7(11): e33022..

    Held, P., Smith, D. L., Bagley, J. M., Kovacevic, M., Steigerwald, V. L., Van Horn, R., & Karnik, N. S. (2021). Treatment response trajectories in a three-week CPT-based intensive treatment for veterans with PTSD. Journal of Psychiatric Research, 141, 226-232.

    Held, P., Coleman, J. A., Petrey, K., Klassen, B. J., Pridgen, S., Bravo, K., Smith, D. L., & Van Horn, R. (2021). A Case Series Examining PTSD and Depression Symptom Reductions over the Course of a 2-Week Virtual Intensive PTSD Treatment Program for Veterans. Psychological Trauma: Theory, Research, Practice, and Policy.

    Held, P., Klassen, B. J., Steigerwald, V. L., Smith, D. L., Bravo, K., Rozek, D. C., Van Horn, R., & Zalta, A. (2021). Do morally injurious experiences and index events negatively impact intensive PTSD treatment outcomes among combat veterans? European journal of psychotraumatology, 12(1), 1877026.

    Post, L. M., Held, P., Smith, D. L., Black, K., Van Horn, R., Pollack, M. H., Rothbaum, B. O., & Rauch, S. A. M. (2021). Impact of intensive treatment programs for posttraumatic stress disorder on suicidal ideation in veterans and service members. Psychological Services, 18(4), 671-678.

    Held, P., Steigerwald, V. L., Smith, D. L., Kaysen, D., Van Horn, R., & Karnik, N. S. (2021). Impact of Hazardous alcohol use on intensive PTSD treatment outcomes among veterans. European Journal of Psychotraumatology, 12(1), 1888541.

    Takuma, T., Matsumoto T, Tabara, Y., Gozal D, Smith D.L., Murase, K., Tanizawa K, Takahashi, N., Nakatsuka, Y., Hamada, S., Handa, T., Takeyama, H., Oga T, Nakamoto, I., Wakamura, T., Komenami, N., Setoh, K., Tsutsumi, T., Kawaguchi, T., Kamatani, Y., Takahashi, Y., Morita, S., Nakayama, T., Harai, T., Matsuta, F., Chin, K. (2021).  Impact of sleep disordered breathing on glucose metabolism among individuals with a family history of diabetes. Journal of Clinical Sleep Medicine, 17(2), 129-140.

    Tirone, V., Smith, D.L., Steigerwald, V., Bagley, J.M., Brennan, M., Van Horn, R., Pollack, M. & Held, P. (2020). Examining the impact of sexual re-victimization in a sample of veterans undergoing intensive PTSD treatment. Journal of Interpersonal Violence, 36 (23), 10989-11008.

    Zalta, A.K., Wagner, L.M., Valdespino-Hayden, Z., Smith, D.L., Burgess, H.J., Held, P., Boley, R.A., Karnik, N.S., Pollack, M.H., (2020). Examining insomnia during intensive treatment for veterans with PTSD: Does it improve and does it predict treatment outcomes? Journal of Traumatic Stress, 33(4).

    Lofgreen, A., Tirone, V., Carroll, C., Rufa, A., Smith, D.L., Bagley, J., Zalta, A., Brennan, M., Van Horn, R., Pollack, M. & Held, P. (2020). Improving outcomes for a 3-week intensive treatment program for Posttraumatic Stress Disorder in survivors of military sexual trauma. Journal of Affective Disorders, 269, 134-140.

    Brockmann, P. E., Poggi, H., Martinez, A., D’Apremont, I., Moore, R., Smith, D., & Gozal, D. (2020). Perinatal antecedents of sleep disturbances in schoolchildren. Sleep, 43(8), zsaa021.

    Held, P., Zalta, A. K., Smith, D. L., Bagley, J. M., Steigerwald, V. L., Boley, R. A., Miller, M., Brennan, M. B., Van Horn, R., & Pollack, M. H. (2020). Maintenance of treatment gains up to 12-months following a three-week cognitive processing therapy-based intensive PTSD treatment program for veterans. European Journal of Psychotraumatology, 11(1), 1789324.

    Held, P., Klassen, B.J., Boley, R.A., Smith, D.L., Wiltsey Stirman, S., Pollack, M.H., Karnik, N.S., Brennan, M.B., Van Horn, R., & Zalta, A.K. (2020). Feasibility of a 3-week Intensive treatment program for service members and veterans with PTSD. Psychological Trauma:Theory, Research, Practice, and Policy, 12(4), 422..

    Glover, A. C., Schueller, S. M., Winiarski, D. A., Smith, D. L., Karnik, N. S., & Zalta, A. K. (2019). Automated mobile phone–based mental health resource for homeless youth: pilot study assessing feasibility and acceptability. JMIR mental health, 6(10), e15144.

    Hirabayashi, M., Smith D.L, An. J. (2019). Biostatistics 101: Perspective on statistics in Opthalmology. JOJ Opthalmology, 7, 5, 001-004.

    Horwitz, A., Smith, D.L., Held, P., Zalta, A.K., (2019). Characteristics of Veteran and Civilian Suicide Decedents: A Sex-stratified Examination of the National Violent Death Reporting System. American Journal of Preventive Medicine, e163-e168.

    Sanchez, T., Gozal, D., Smith, D.L., Foncea, C., Betancur, C., Brockmann, P. (2019). Association between air pollution and sleep disordered breathing in children. Pediatric Pulmonology, 1-7.

    Metz, J.E., Attarian, H.P., Harrison, M.C., Blank, J., Takacs, C.M., Baron, K.G., Smith, D. L, & Gozal, D. (2019). High-resolution pulse oximetry and titration of a mandibular advancement device for obstructive sleep apnea. Efficacy of Mandibular Advancement Device for the Treatment of Obstructive Sleep Apnea. Frontiers in Neurology, 10, 757.

    Zalta, A. K., Held, P., Smith, D. L., Klassen, B. J., Lofgreen, A. M., Normand, P. S., Brennan, M. B., Rydberg, T. S., Boley, R. A., Pollack, M. H., Karnik, N. S. (2018). Evaluating patterns and predictors of symptom change during a three-week intensive outpatient treatment for veterans with PTSD. BMC Psychiatry, 1, 242.

    Carroll, K. K., Lofgreen, A. M., Weaver, D. C., Held, P., Klassen, B.J., Smith, D.L., Karnik, N.S., Pollack, M.H., Zalta, A.K. (2018). Negative posttraumatic cognitions among military sexual trauma survivors. Journal of Affective Disorders, 238, 88-93.

    Piche, J., Kaylegian, J., Smith, D.L., & Hunter, S.J. (2018). The relationship between self- reported executive functioning and risk-taking behavior in urban homeless youth. Behavioral Sciences, 8, 6. doi:10.3390/bs8010006 

    Matsumoto, T., Murase, K., Tabara, Y., Gozal, D., Smith, D.L., Minami, T., Tachikawa, R.,Tanizawa, K., Oga, T., Nagashima, S., Wakamura, T., Komenami, N., Setoh, K., Kawaguchi, T., Tsutsumi, T., Takahaski, Y., Nakayama, T., Harai, T., Matsuda, F., & Chin, K., (2018). Impact of sleep characteristics and obesity on diabetes and hypertension across genders and menopausal status: The Nagahama study. Sleep, doi: 10.1093/sleep/zsy071. [Impact factor: 5.135]

    Smith, D.L., Gozal, D., Hunter, S. & Kheirandish-Gozal, L. (2017). Snoring frequency, rather than AHI, predicts both cognitive and behavioral problems in young children. Sleep Medicine, 34, 170-178. doi:10.1016/j.sleep.2017.02.027

    Sakamoto, N., Gozal, D., Smith, D.L., N., Yang, L., Morimoto, N., Wada, H., Maruyama, K., Maruyama, A., Suzuki, Y., Nakayama, M., Horiguchi, I., Tanigawa, T. (2017). Sleep duration, snoring prevalence, obesity, and behavioral problems in a large cohort of primary school students in Japan. Sleep, 40, 1-8.

    Smith, D.L., Gozal, D., Hunter, S. & Kheirandish-Gozal, L. (2017). Response to  commentary: Parent- reported behavioral and psychiatric problems mediate the relationship between sleep disordered breathing and cognitive deficits in school-aged children. Frontiers in Neurology.9, 63.

    Gozal, D., Khalyfa, A., Qiao, Z., Smith, D.L., Philby, M.F., Koren, D., Kheirandish-Gozal, L. (2017). Angiopoietin 2 and Soluble Tie-2 Receptor Plasma Levels in Children with Obstructive Sleep Apnea and Obesity. Obesity, 25, 1083-1090. doi:10.1002/oby.21859

    Smith, D.L., Gozal, D., Hunter, S. & Kheirandish-Gozal, L. (2017). Parent- reported behavioral and psychiatric problems mediate the relationship between sleep disordered breathing and cognitive deficits in school-aged children. Frontiers in Neurology, 8, 410. doi: 10.3389/fneur.2017.00410

    Brockmann, P.E., Damiani, F., Smith, D.L., Castet, A., Nunez, F., Villarroel, L. & Gozal, D. (2016). Metabolic consequences of sleep-disordered breathing in adolescents and younger adults: A population study in Chile. International Journal of Obesity, 40(10), 1510-1514.

    Smith, D.L., Gozal, D., Hunter, S.J., Philby, M.F., Kaylegian, J., & Kheirandish-Gozal, L. (2016). The impact of sleep-disordered breathing on behavior among elementary school-aged children: A cross-sectional analysis of a large community-based sample. European Respiratory Journal, 48, 1631-1639.

    Hunter, S.J., Gozal, D., Smith, D.L., Philby, M.F., Kaylegian, J., & Kheirandish-Gozal, L. (2016). Effect of Sleep-Disordered breathing severity on cognitive performance measures in a large community cohort of young school-aged children. American Journal of Respiratory and Critical Care Medicine, 194, 739-747.

    Castro, A. L., Gustafson, E. L., Ford, A. E., Edidin, J. P., Smith, D. L., Karnik, N. S., & Hunter, S. J. (2014). Psychiatric disorders, high-risk behaviors, and chronicity of episodes among predominantly African American homeless Chicago youth. Journal of Health Care for the Poor and Underserved, 25, 1201-1216.

    Smith, D. L., Cook, P., & Buskist, W. (2011). An experimental investigation into the effects of assigned grades on teaching evaluations. Teaching of Psychology, 38, 225-228.

    Smith, D. L., & Barker, L. (2008). Using yes-no recognition tests to assess student memory for course content. Teaching of Psychology, 35, 319-326.

    Keeley, J. W., Smith, D. L., & Buskist, W. (2006). The Teacher Behavior Checklist: Factor analysis of its utility for evaluating teaching effectiveness. Teaching of Psychology, 33, 84-91.