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  2. Tory Eisenlohr-Moul

Tory Eisenlohr-Moul PhD

Tory Eisenlohr-Moul
Designation
  • Assistant Professor of Psychiatry and Psychology
  • Associate Director of Translational Research in Women’s Mental Health
  • Department of Psychiatry
  • University of Illinois at Chicago College of Medicine
Contact Information
  • temo [at] uic.edu
  • Neuropsychiatric Institute (NPI)
    912 S. Wood St.
    Department of Psychiatry (MC 913)
    Chicago IL 60612
  • Room #:335
Website

Dr. Eisenlohr-Moul is an Assistant Professor of Psychiatry at UIC, and holds an additional courtesy appointment in the Department of Psychology.  She is a licensed clinical psychologist with specialized fellowship training in the pathophysiology, assessment, and treatment of hormone-related psychiatric disorders-- particularly premenstrual disorders.

As a scientist, she works primarily with mechanistic randomized controlled trials (RCTs) and longitudinal observation studies to clarify how ovarian steroids alter transdiagnostic RDoC constructs (e.g., arousal, processing of loss or threat) and related phenotypes (particularly suicidality and alcohol use) in susceptible females. Her NIMH-funded clinical trials (K99109667; R00MH109667; RF1MH120843) examine the effects of natural changes in neuroactive steroids (vs. exogenous steroid stabilization) on mechanisms of proximal suicide risk during the perimenstrual weeks of the menstrual cycle. She has also been awarded a NARSAD Young Investigator Grant to evaluate the role of the immune system in these effects. 

Recently, she has also engaged in collaborative grants to study the role of the menstrual cycle in (1) adolescent suicidal ideation and behavior (R01MH122446; Role: Principal Investigator), (2) alcohol use (R21AA028736; Role: consultant), and (3) symptoms of ADHD (R01MH119119; Role: Co-I). She is passionate about training and empowering others to conduct rigorous scientific work on the menstrual cycle and mental health.

Over the past five years, she has also volunteered as the Chair of the Clinical Advisory Board at the International Association for Premenstrual Disorders (IAPMD), a nonprofit that seeks to educate patients, health care providers, and scientists about premenstrual disorders, and to advocate for scientific, healthcare, and policy progress in this area. This work has culminated in the organization’s recent receipt of a 2021 PCORI stakeholder convening grant to bring together scientific, healthcare, and patient stakeholders to discuss the current state of the premenstrual disorders landscape and make recommendations for patient-informed science in this area as the field moves forward.

The combination of her scientific contributions and advocacy work has established her as an international expert in the pathophysiology, assessment, and treatment of premenstrual dysphoric disorder and cyclical exacerbation of other psychiatric disorders.

  • psychiatry

    Menstrual cycle effects on mental health, perimenopausal depression (menopause), postpartum depression (pregnancy), perinatal mental health, reproductive mood disorders, estrogen, estradiol, progesterone, testosterone, allopregnanolone, GABAergic neurosteroids, allopregnanolone, psychoneuroendocrinology, reproductive psychiatry, suicide, suicidal behavior, non-suicidal self-injury, substance use, addiction, interpersonal functioning, impulsive and compulsive disorders, premenstrual dysphoric disorder (PMDD), perimenstrual exacerbation of underlying disorder (PME), borderline personality disorder (BPD), assessment and diagnosis, Dialectical Behavior Therapy (DBT), women’s mental health

  • Eisenlohr‐Moul, T. A. Commentary on Joyce et al.: Studying menstrual cycle effects on behavior requires within‐person designs and attention to individual differences in hormone sensitivity. Addiction.

    Schmalenberger, K. M., Tauseef, H. A., Barone, J. C., Owens, S. A., Lieberman, L., Jarczok, M. N., ... & Eisenlohr-Moul, T. A. (2020). How to study the menstrual cycle: Practical tools and recommendations. Psychoneuroendocrinology, 104895.

    Eisenlohr-Moul, T. (2019). Premenstrual disorders: a primer and research agenda for psychologists. The Clinical psychologist, 72(1), 5.

    Eisenlohr-Moul, T. A., Girdler, S. S., Schmalenberger, K. M., Dawson, D. N., Surana, P., Johnson, J. L., & Rubinow, D. R. (2017). Toward the reliable diagnosis of DSM-5 premenstrual dysphoric disorder: the Carolina Premenstrual Assessment Scoring System (C-PASS). American Journal of Psychiatry, 174(1), 51-59.

    Eisenlohr-Moul, T. A., Kaiser, G., Weise, C., Schmalenberger, K. M., Kiesner, J., Ditzen, B., & Kleinstäuber, M. (2020). Are there temporal subtypes of premenstrual dysphoric disorder?: using group-based trajectory modeling to identify individual differences in symptom change. Psychological medicine, 50(6), 964-972.

    Eisenlohr-Moul, T. A., Schmalenberger, K. M., Owens, S. A., Peters, J. R., Dawson, D. N., & Girdler, S. S. (2018). Perimenstrual exacerbation of symptoms in borderline personality disorder: evidence from multilevel models and the Carolina Premenstrual Assessment Scoring System. Psychological medicine, 48(12), 2085.

    Owens, S. A., & Eisenlohr-Moul, T. (2018). Suicide risk and the menstrual cycle: a review of candidate RDoC mechanisms. Current psychiatry reports, 20(11), 1-11.

Title Description Investigator(s) Category Status
Adolescent Girls’ Risk for Suicide Across the Menstrual Cycle: Examining Stress and Negative Valence Systems Longitudinally R01-NIMH-122446 Examining the impact of the adolescent menstrual cycle on suicidal thoughts and behaviors. CLEAR – Eisenlohr-Moul Lab On-going
Cyclical Neuroactive Steroid Changes, Arousal, and Proximal Suicide Risk: An Experimental Approach R01-NIMH-120843 Experimentally delineating the neurosteroid pathways which may be involved in perimenstrual worsening of depression and suicide risk.  CLEAR – Eisenlohr-Moul Lab On-going
Estrogen Effects on ADHD and Cognition R01-NIMH-119119 Examining the potential role of estrogen fluctuations across the menstrual cycle in symptoms of attention deficit hyperactivity disorder (ADHD).  CLEAR – Eisenlohr-Moul Lab On-going
Influence of synthetic sex hormones on alcohol effects in women? In these projects, we use human laboratory procedures to study how natural and synthetic sex hormones influence alcohol subjective and behavioral effects in women. The HAPPY Lab On-going
Ovarian Hormone Withdrawal and Suicide Risk: An Experimental Approach K99/R00-NIMH-109667 Experimentally delineating the causal role of perimenstrual withdrawal from estradiol, progesterone, and their combination in acute suicide risk. CLEAR – Eisenlohr-Moul Lab On-going
Measuring Inflammatory Reactivity as a Mediator of Early Adversity’s Effects on Interpersonal Dysfunction in Women Mind and Life Foundation The purpose of this study is to examine, in the context of a randomized controlled trial of mindfulness-based stress reduction, the unique effects of mindfulness training on inflammatory responses to psychosocial stress among females with and without early life abuse.  CLEAR – Eisenlohr-Moul Lab Completed
Using a Perimenstrual Steroid Stabilization Experiment to Validate a Smartphone-Based Assessment Protocol for Perimenstrual Mood Dysregulation and Suicidality Gia Allemand Foundation CLEAR – Eisenlohr-Moul Lab Completed