Dr. John Davis named the 2025 Lifetime Achievement Awardee from the Schizophrenia International Research Society

Dr. John M Davis is professor of psychiatry at the University of IL at Chicago. He began his career as a clinical associate at NIH, and, with William Bunney, reviewed evidence that biogenic amines may be decreased in depression, which was published one month after Dr. Schildkraut’s seminal paper. Dr. Davis, in collaboration with Steve Curry, did the first studies of antipsychotic plasma levels in man (1969), showing plasma levels are associated with side effects. They found much higher plasma levels after intramuscular administration than oral administration, an elucidation of first-pass metabolism, where oral medication is extensively metabolized in its first pass through the liver. Davis also described several drug-drug interactions.