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WMHRP Currently Funded Research

Listed below are the active research studies led by Women’s Mental Health Research Program’s Principal Investigators (PIs) that receive internal or external funding support. The WMHRP team also conducts research with many collaborators throughout UIC, locally and nationally. Current collaborative research projects are also listed below.

If you are interested in participating in research, please visit our Participate in Research page.

 

Menopause and the Menopausal Transition

Menopausal Vasomotor Symptoms and Brain Aging in Women
Co-PI: Pauline Maki, PhD and Rebecca Thurston, PhD
This multi-year R01 equivalent grant examines the relationship between vasomotor symptoms, the cardinal symptom of menopause, and structural and functional integrity of the brain and cognitive function. This study is funded by the National Institute on Aging (NIA - RF1 AG053504).

 

Stellate Ganglion Blockade for the Management of Vasomotor Symptoms
PI: David Walega, MD
Co-I: Pauline Maki, PhD and Leah Rubin, PhD, MPH
This multi-year grant supports a randomized, sham-controlled clinical trial of stellate ganglion blockade on vasomotor symptoms in midlife women. Secondary outcomes include cognition, mood, brain imaging outcomes, and autonomic nervous system activity. This study is funded by the National Institute on Aging (NIA - R01 AG049924).

 

HIV

WIHS: Women’s Interagency HIV Study

Neurocognitive Research in Women’s Interagency HIV Study (WIHS), Chicago Consortium
PIs: Pauline Maki, PhD
This is an ongoing program of research to investigate the predictors of neurocognitive function and HIV Associated Neurocognitive Disorders (HAND) in HIV-infected women in the Women’s Interagency HIV Study (WIHS) Chicago Consortium. The WIHS is a multi-site prospective epidemiology cohort study of women who either are infected with HIV or are at increased risk for acquiring HIV infection. The WIHS is primarily funded by the National Institute of Allergy and Infectious Diseases (NIAID), with co-funding from the National Institute of Mental Health (NIMH), the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), National Cancer Institute (NCI), and National Institute on Drug Abuse (NIDA).

 

Effects of Glucocorticoids on Cognitive Functioning in HIV-infected Women
PI: Leah Rubin, PhD, MPH
Co-I: Pauline Maki, PhD
This R01 grant examines the effects of low-dose hydrocortisone (LDH) on cognition in HIV+ women with the goal to identify and assess an adjunctive therapy for the treatment of cognitive dysfunction in HIV+ women. This study is funded by the National Institute on Mental Health (NIMH -- R01 MH113512 ).

 

Pregnancy

Enhancing Perinatal Mental Health: A Feasibility Study of a Collaborative, Translational Research Approach
PI: Pauline Maki, PhD
Co-I: Leah Rubin, PhD, Jack Gilbert, PhD, Lisa Tussing-Humphreys, PhD, Beatriz Penalver Bernabe, PhD
The project goals include: (1) Piloting a randomized controlled trial of a provider training program to improve screening, assessment, and referral procedures for perinatal depression and anxiety disorders during clinical visits; and (2) Establishing an enduring database linking perinatal depression and anxiety diagnoses, medical records, and a biorepository of blood samples from routine perinatal clinic visits. This research is funded by the University of Illinois at Chicago Chancellor’s Fund.

 

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