University of Illinois at Chicago
Department of Psychiatry (M/C 912),
Psychiatric Institute Room 466,
1601 West Taylor Street,
Chicago, IL 60612,
Office Phone: 312-355-1593
1. Dutton, J.W., Chen, H., You, C., Brodie, M.S. & Lasek, A.W. (2016). Anaplastic lymphoma kinase (ALK) regulates binge-like drinking and dopamine receptor sensitivity in the ventral tegmental area. Addiction Biology. Jan 11 epub ahead of print. doi: 10.1111/adb.12358. PMC Journal-In Process.
2. Chen, H., He, D., & Lasek, A.W. (2015). Repeated Binge Drinking Increases Perineuronal Nets in the Insular Cortex. Alcohol. Clin. Exp. Res., 39(10):1930-8. PMCID: PMC4592458.
3. He, D., Chen, H., Muramatsu, H., & Lasek, A.W. (2015). Ethanol activates midkine and anaplastic lymphoma kinase signaling in neuroblastoma cells and in the brain. J. Neurochem., 135(3):508-21. PMCID: PMC4618084.
4. Savarese, A., Zou, M.E., Kharazia, V., Maiya, R., & Lasek, A.W. (2014). Increased behavioral responses to ethanol in Lmo3 knockout mice. Genes, Brain and Behavior 13(8), 777-83. PMCID: PMC4442799
5. Lasek, A.W., Lim, J., Kliethermes, C.L., Berger, K.H., Joslyn, G., Brush, G., Xue, L., Robertson, M., Moore, M.S., Vranizan, K., Morris, S.W., Schuckit, M.A., White, R.L., & Heberlein, U. (2011). An evolutionary conserved role for anaplastic lymphoma kinase in behavioral responses to ethanol. PLoS One, 6(7), e22636. PMCID: PMC3142173.
See more of my publications at NCBI.
Amy W. Lasek, PhD
Assistant Professor of Psychiatry
Assistant Professor of Anatomy and Cell Biology
Member, Graduate Program in Neuroscience
Dr. Lasek is interested in the molecular and cell biological factors that contribute to alcohol use disorders and drug addiction. She graduated from Case Western Reserve University with a BA in Biology and Biochemistry and received her PhD in Molecular Biology from Cornell University. Prior to joining the Department of Psychiatry at UIC, Dr. Lasek was an Associate Investigator at the Ernest Gallo Clinic and Research Center at the University of California, San Francisco, where she cultivated her interests in molecular neuroscience and addiction research.
Dr. Lasek’s research is focused on determining how perturbing signaling pathways and gene expression in the brain alters behaviors related to drug and alcohol addiction. The laboratory uses molecular genetic techniques in the mouse to answer these questions. Dr. Lasek is also particularly interested in elucidating the neurobiological basis for sex differences in drug abuse. The overall goal of her research is to find and define new signaling pathways in the brain to better understand drug reward and abuse.
Molecular neurobiology of alcohol and drug addiction, effects of estrogen on reward and addiction-related behaviors.
International Behavioral and Neural Genetics Society
Research Society on Alcoholism
NIH/NIAAA INIA-West Consortium, RNA Interference Core
NIH/NIAAA INIA-West Consortium, Regulation of Excessive Alcohol Consumption by the LMO-ALK Axis
NIH/NIDA, Mechanisms of Estrogen Action in Enhancing Behavioral Responses to Cocaine.