Sean Conrin, M.D. and Robert Marvin M.D. are Co-Directors of the Metabolic Monitoring Clinic. It is well known that persons with psychiatric disorders have high rates of comorbidity for weight gain, diabetes and high cholesterol associated with the treatment with second-generation antipsychotic agents (SGA). Of major concern, coronary heart disease is among the primary causes of a 20% decreased life-expectancy among patients with schizophrenia compared to the general population. The Psychosis Treatment Program offers on-site medical evaluations and monitoring of weight, blood pressure, blood sugar, and cholesterol. Aneet Ahluwalia M.D., a dual certified Psychiatrist and Internal Medicine specialist is available during the Psychosis Treatment Program Medication Clinic to provide general medical care. Appointments to see Dr. Ahluwalia can be scheduled on the same day as your appointment with your psychiatrist.
The Colbeth Clinic was established within the Institute of Juvenile Research at the University of Illinois at Chicago (UIC) College of Medicine in 2000 with the generosity of Doug and Margaret Colbeth. Doug Colbeth is president, chief executive officer and chairman of the board of Kinaxis™. As one of the true visionaries of the Internet explosion in the mid 1990's, prior to Kinaxis, Doug was chief executive officer of Spyglass Inc., a leading provider of Internet software technologies. Spyglass technologies are utilized inside millions of products including PCs, televisions, telephones, and other hand-held devices. Most notably, Spyglass technology is the foundation of the Microsoft Internet Explorer browser.
The Colbeth's awareness of the great costs and pain that can occur due to child mental illnesses and the great hope and capability that can come from effective treatment led Doug and his wife Margaret to work with IJR, and together they took on the commitment that is the mission of the Colbeth Clinic—to raise awareness, provide early diagnosis and offer effective treatments of biological brain disorders, and to help ensure that the advanced care of the clinic is available to children and families irrespective of means or circumstance.
Raising awareness and erasing the stigma associated with mental health disorders is one of the key objectives of the clinic and a personal mission of the Colbeths. As in his early work in the Internet development, Doug and Margaret are visionaries who are determined to innovate and transform children’s mental health awareness, knowledge, and care.
"Like millions of teens, I personally experienced the quiet desperation of severe depression," says Doug Colbeth. "Fortunately, I was able to get excellent treatment before something tragic happened. This is precisely what we want to provide to others, especially those who may not have the financial means or access to best-of-class mental health services.
I believe we must come out of the shadows to share our personal experiences and let our stories resonate with those among us who are, or know of someone that is suffering. Erasing the stigma will increase funding for the cause, encourage additional talented people to enter the field, and most importantly, encourage patients to seek treatments earlier. Only when we acknowledge how common mental health disorders are, can we make real progress in the treatment of these diseases."
The Institute for Juvenile Research extends thanks to Doug and Margaret Colbeth for supporting the Colbeth Child and Adolescent Psychiatry Clinic with their generous donation.
University of Illinois at Chicago
Department of Psychiatry (M/C 747)
Institute for Juvenile Research
1747 W. Roosevelt Road, Rm. 155
Chicago, IL 60608
Office Phone: (630) 428-6106
Office Fax: (630) 428-6101
Assistant: Darnetta Byndum,
Atkins, M. S., Frazier, S. L., Leathers, S. J., Graczyk, P. A. et al (in press). Teacher key opinion leaders and mental health consultation in urban low-income schools. Journal of Consulting and Clinical Psychology.
Graczyk, P. A., & Connolly, S. D. (2008). Anxiety disorders in childhood. In T. Gullotta (Ed.), Handbook of child behavioral issues: Evidence- based approaches (pp. 215-238). New York: Taylor and Francis, Publishers.
Graczyk, P. A., Domitrovich, C. E., Small, M., & Zins, J. E. (2006). Serving all children: An implementation model framework. School Psychology Review, 35, 266-274.
Graczyk, P. A., Atkins, M. S., Jackson, M. M., Letendre, J. A., Kim, J. Y. S., Baumann, B. L., & McCoy, J. (2005). Urban educators' perceptions of interventions for Attention Deficit Hyperactivity Disorder: A preliminary investigation. Behavioral Disorders, 30, 95-104.
Pavuluri, M. N., Graczyk, P. A., Henry, D. B., Carbray, J. A., Heidenreich, J., & Miklowitz, D. J. (2004). Child and family-focused cognitive behavioral therapy for pediatric bipolar disorder: Development and preliminary results. Journal of the American Academy of Child and Adolescent Psychiatry, 43 (5), 528-537.
Elias, M. J., Zins, J. E., Graczyk, P. A., & Weissberg, R. P. (2003). Implementation, sustainability, and scaling up of social-emotional and academic innovations in public schools. School Psychology Review, 32 (3), 313-319.
Lovejoy, M. C., Graczyk, P. A., O'Hare, E., & Neuman, G. (2000). Maternal depression and parenting behavior: A meta-analytic review. Clinical Psychology Review, 20, 561-592.
Graczyk, P. A., Domitrovich, C. E, & Zins, J. E. (2003). Facilitating the implementation of evidence-based prevention and mental health promotion efforts in schools. In M. D. Weist, S. W. Evans, & N. A. Lever (Eds.), Handbook of school mental health: Advancing practice and research, (pp. 301- 318). New York: Kluwer Academic/ Plenum Publishers.
Waas, G. A., & Graczyk, P. A. (2000). Child behaviors leading to peer rejection: A view from the peer group. Child Study Journal, 29, 291-306.
Waas, G. A., & Graczyk, P. A. (1998). Group interventions for the peer-rejected child. In K. C. Stoiber and T. R. Kratochwill (Eds.), Handbook of group intervention for children and families (pp. 141-158). Boston: Allyn & Bacon.
Patricia A. Graczyk, PhD
Assistant Professor of Clinical Psychology
Dr. Graczyk earned her PhD in Clinical Psychology and School Psychology from Northern Illinois University in 1998 and completed a National Institute of Mental Health (NIMH) postdoctoral prevention research fellowship in urban children's mental health in 2001. Her work at UIC allows her to combine her research and clinical interests in anxiety disorders with her desire to continue to work with schools and community agencies in providing quality mental health services to children.
Dr. Graczyk has presented at professional local, national, and international conferences on such topics as pediatric anxiety disorders, Asperger's Disorder, school-based mental health services, social and emotional learning (SEL), child and adolescent peer relationships, and the role of key opinion leader teachers in promoting the utilization of school-based interventions for children with ADHD. She has written journal articles and book chapters on an array of topics. Dr. Graczyk's most recent research is focused on determining ways to help community-based mental health practitioners (e.g., in schools and community mental health agencies) learn and use evidence-based mental health interventions with the children and families they serve, especially youth with anxiety disorders.
Dr. Graczyk is a licensed clinical psychologist and a certified school psychologist. She works as a school psychologist in Indian Prairie School District 204 in Naperville, Illinois. Dr. Graczyk provides diagnostic and treatment services to children and adolescents with a variety of conditions including anxiety disorders, mood disorders, ADHD, learning disabilities, autism, and Asperger's disorder. She serves as a consultant to parents and educators and presents inservice professional development activities to school personnel on a variety of topics including bullying prevention, problem-solving, data-based decision making, curriculum-based measurement, Positive Behavioral Interventions and Supports (PBIS), and interventions for students with anxiety disorders, ADHD, and nonverbal learning disabilities.
School-based mental health services for children in urban poverty; models for effective community mental health services; dissemination of evidence-based practices
- Association for Positive Behavioral Supports
- National Association of School Psychologists
- Illinois School Psychologists' Association (Charter Member)
Training Community Mental Health Professionals in Evidence-Based Practices for Children and Adolescents Social Support for Children with Anxiety Disorders
Disruptive Behavior Disorders School-Age Service (DBS)
The DBD Program has a mission of designing, delivering, and developing state-of-the-art mental health interventions for children and families with externalizing disorders and co-morbid diagnoses.
The School-Age Disruptive Behavior Disorders (DBS) Service provides evidence-based outpatient treatments to families of school-age youth who are diagnosed with disruptive behaviors including Oppositional Defiant Disorder (ODD) and/or Conduct Disorder (CD) with co-morbid diagnoses including Attention Deficit Hyperactivity Disorder (ADHD) and Post-Traumatic Stress Syndrome (PTSD). The School-Age Service uses a family-focused intervention approach combining group and family therapy modalities for children, adolescents, and parents. This family-focused intervention approach emphasizes evidence-based, ecologically-appropriate, and culturally-sensitive practices that integrate clinic-based and community-based services (e.g., clinical interventions for homes, schools, neighborhoods, youth centers, etc.).
The clinical research team is led by Karen Taylor-Crawford, MD Director and Assistant Professor of Clinical Psychiatry; Jaleel Abdul-Adil, PhD, Associate Professor of Clinical Psychology; and Carl Bell, MD, CEO of Community Mental Health Council and Professor of Psychiatry and Public Health.
The goals of the Psychiatric Institute (PI), which is directed by Dr. Alessandro Guidotti, are to investigate the role of epigenetic mechanisms in regulating neuronal gene expression in the brain. The reversible modulation of gene function mediated through changes in DNA methylation and histone modifications is tightly regulated and is responsible for coordinating neuronal structure and function during development and in the adult. The programmatic focus is to examine DNA methylation marks and histone modifications as related to altered transcription profiles of sets of genes in the course of schizophrenia and autism. At a recent Society for Neuroscience Symposium lecture, Dr. Dennis R. Grayson, spoke about his ongoing efforts in studying DNA methylation and hydroxymethylation patterns in DNA from post-mortem cerebella from autism spectrum disorder subjects. In addition to the use of post-mortem brain specimens, researchers at the PI, including Drs. Erbo Dong and James Auta, are studying the effects of prenatal stress in animals as a means of modeling psychiatric behaviors in rodents. Collectively, we are investigating mechanisms by which psychiatrists may be able to reverse altered gene expression programs in the brain through the development of new pharmaceutical strategies. Another program being explored by Drs. Rajiv P. Sharma and John M. Davis involves examining DNA methylation of schizophrenia and non-psychiatric subjects for the presence of epigenetic biomarkers that may be useful in detecting schizophrenia at early stages of the disorder. The hope is to use this information for the development of hypothesis-designed pharmaceuticals aimed at altering chromatin structure.
In addition to the above studies, research at the PI includes studies of basic aspects of neuronal function and neuronal circuitry in vitro and in vivo. Dr. John Larson studies the cellular and molecular mechanisms of memory formation. Dr. Neil Smalheiser is examining endogenous siRNAs and noncoding RNA-derived small RNAs expressed in adult mouse hippocampus. Dr. Graziano Pinna investigates mouse models of post-traumatic stress disorder (PTSD); investigating the mechanism of action of antidepressants. Dr. Lech Kiedrowski studies intracellular zinc homeostasis in hippocampal neurons. Dr. Ghanshyam Pandey, Professor in the Department of Psychiatry and Director of Mood Disorders and Suicide Research, is also a member of the PI and he makes a significant contribution in research related to depression, bipolar illness, and suicide.