Heide Klumpp, PhD

Heide Klumpp
Mood & Anxiety Disorders Research Program Department of Psychiatry
University of Illinois at Chicago
Room No. 246,
1747 W. Roosevelt Rd. (MC 747),
Chicago, IL 60608
Office Phone:312-996-0416
E-mail: This email address is being protected from spambots. You need JavaScript enabled to view it.


Klumpp, H., Post D, Angstadt M., Fitzgerald, D.A., Phan, K.L. (in press). Anterior cingulate cortex and insula response during indirect and direct processing of emotional faces in generalized social anxiety disorder. Biology of Mood & Anxiety Disorders.

Klumpp, H., Fitzgerald, D.A., Phan, K.L. (2013). Neural predictors and mechanisms of cognitive behavioral therapy on threat processing in social anxiety disorder. Progress in Neuro-Psychopharmacology & Biological Psychiatry, 45, 83-91

Klumpp, H., Angstadt, M., & Phan, K.L. (2012). Shifting the focus of attention modulates amygdala and anterior cingulate cortex reactivity to emotional faces. Neuroscience Letters, 514, 210-213.

Klumpp, H., Angstadt, M., & Phan, K.L. (2012). Insula reactivity and connectivity to anterior cingulate cortex when processing threat in generalized social anxiety disorder. Biological Psychology, 89, 273-276.

Klumpp, H., Ho, S., Taylor, S.F., Phan, K.L., Abelson, J.L., & Liberzon, I. (2011). Trait anxiety modulates anterior cingulate activation to threat interference. Depression and Anxiety, 28, 194-201.

Klumpp, H., Angstadt, M., Nathan, P.J., & Phan, K.L. (2010). Amygdala reactivity to faces at varying intensities of threat in generalized social phobia: An event-related functional MRI study. Psychiatry Research: Neuroimaging, 183, 167-169.

Klumpp, H., & Amir, N. (2010). Preliminary study of attention training to threat and neutral faces on anxious reactivity to a social stressor in social anxiety. Cognitive Therapy and Research, 34, 263-271.

Klumpp, H., Keller, J., Miller, G.A., Casas, B.R., Best, J.L., & Deldin, P.J. (2010). Semantic processing of emotional words in depression and schizophrenia. International Journal of Psychophysiology, 75, 211–215.

Amir, N., Beard, C., Taylor, C.T., Klumpp, H., Elias, J., Burns, M., & Chen, X. (2009). Attention training in individuals with generalized social phobia: A randomized trial. Journal of Consulting and Clinical Psychology, 77, 961-973.

Shah, S.G., Klumpp, H., Angstadt, M., Nathan, P.J., & Phan, K.L. (2009). Amygdala and insula response to emotional images in generalized social anxiety disorder. Journal of Psychiatry and Neuroscience 34, 296-302.

Heide Klumpp, PhD

Assistant Professor

Dr. Klumpp’s primary research interest is brain pathophysiology in anxiety and depression in the context of emotion, attention, and cognitive-affective processes for clinical translation.  She uses functional magnetic resonance imaging and electroencephalography to delineate brain markers of therapeutic response to psychotherapy to compare with other interventions to evaluate mechanisms of change and to translate discoveries from basic neuroscience into techniques to enhance therapies for internalizing disorders.  The overarching goal is to increase therapeutic response with available treatment and develop more individually-tailored, novel interventions. 


Brain mechanisms of emotion processing and regulation in anxiety and depression
Brain markers of treatment response in anxiety and depression
Information processing disturbances in internalizing disorders


Society of Biological Psychiatry
American Psychological Association
Anxiety and Depression Association of America


Brain Mechanisms of Cognitive Behavioral Therapy for Anxiety Disorders and Depression
Negative Valence Brain Targets and Predictors of Anxiety and Depression Treatment
Sleep Disturbance in Mood Disorders Across the Lifespan


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