Pauline Maki


University of Illinois at Chicago
Department of Psychiatry
Neuropsychiatry Institute
912 S. Wood Street, Room-328
Chicago, IL 60612

Office Phone: (312) 996-6941
E-mail: This email address is being protected from spambots. You need JavaScript enabled to view it.

North American Menopause Society

Chicago Developmental Center for AIDS Research

Women’s Interagency HIV Study


1: Weber MT, Maki PM, McDermott MP. Cognition and mood in perimenopause: A systematic review and meta-analysis. J Steroid Biochem Mol Biol. 2013 Jun 13. doi:pii: S0960-0760(13)00111-8. 10.1016/j.jsbmb.2013.06.001. [Epub ahead of print] PubMed PMID: 23770320.

2: Maki PM. Critical window hypothesis of hormone therapy and cognition: a scientific update on clinical studies. Menopause. 2013 Jun;20(6):695-709. doi:10.1097/GME.0b013e3182960cf8. PubMed PMID: 23715379.

3: Drogos LL, Rubin LH, Geller SE, Banuvar S, Shulman LP, Maki PM. Objective cognitive performance is related to subjective memory complaints in midlife women with moderate to severe vasomotor symptoms. Menopause. 2013 May 13. [Epub ahead of print] PubMed PMID: 23676633.

4: Weber MT, Rubin LH, Maki PM. Cognition in perimenopause: the effect of transition stage. Menopause. 2013 May;20(5):511- 7. doi: 10.1097/GME.0b013e31827655e5. PubMed PMID: 23615642.

5: J Meyer V, Rubin LH, Martin E, Weber KM, Cohen MH, Golub ET, Valcour V, Young MA, Crystal H, Anastos K, Aouizerat BE, Milam J, Maki PM. HIV and recent illicit drug use interact to affect verbal memory in women. J Acquir Immune Defic Syndr. 2013 May 1;63(1):67-76. doi: 10.1097/QAI.0b013e318289565c. PubMed PMID: 23392462;PubMed Central PMCID: PMC3628722.

6: Weber MT, Rubin LH, Maki PM. Cognition in perimenopause: the effect of transition stage. Menopause. 2013 Jan 2. [Epub ahead of print] PubMed PMID:23287890; PubMed Central PMCID: PMC3620712.

7: Maki PM, Rubin LH, Cohen M, Golub ET, Greenblatt RM, Young M, Schwartz RM, Anastos K, Cook JA. Depressive symptoms are increased in the early perimenopausal stage in ethnically diverse human immunodeficiency virus-infected and humanimmunodeficiency virus-uninfected women. Menopause. 2012 Nov;19(11):1215-23. doi: 10.1097/gme.0b013e318255434d. PubMed PMID: 22872013; PubMed Central PMCID: PMC3483358.

8: Maki PM. Minireview: effects of different HT formulations on cognition. Endocrinology. 2012 Aug;153(8):3564-70. doi: 10.1210/en.2012-1175. Epub 2012 Jun 6. Review. PubMed PMID: 22673228.

9: Weber MT, Mapstone M, Staskiewicz J, Maki PM. Reconciling subjective memory complaints with objective memory performance in the menopausal transition.Menopause. 2012 Jul;19(7):735-41. doi: 10.1097/gme.0b013e318241fd22. PubMed PMID:22415562.

10: North American Menopause Society (Maki PM). The 2012 hormone therapy position statement of: The North American Menopause Society. Menopause. 2012 Mar;19(3):257-71. doi: 10.1097/gme.0b013e31824b970a. PubMed PMID: 22367731; PubMed Central PMCID:PMC3443956.

11: Harlow SD, Gass M, Hall JE, Lobo R, Maki P, Rebar RW, Sherman S, Sluss PM, de Villiers TJ; STRAW 10 Collaborative Group. Executive summary of the Stages of Reproductive Aging Workshop + 10: addressing the unfinished agenda of staging reproductive aging. Menopause. 2012 Apr;19(4):387-95. doi:10.1097/gme.0b013e31824d8f40. PubMed PMID: 22343510; PubMed Central PMCID:PMC3340903.

12: Domino SE, Bodurtha J, Nagel JD; BIRCWH Program Leadership (Maki PM). Interdisciplinary research career development: building interdisciplinary research careers in women's health program best practices. J Womens Health (Larchmt). 2011 Nov;20(11):1587-601. doi: 10.1089/jwh.2011.3165. Epub 2011 Sep 16. PubMed PMID:21923414; PubMed Central PMCID: PMC3216063

13: Rubin LH, Cook JA, Grey DD, Weber K, Wells C, Golub ET, Wright RL, Schwartz RM, Goparaju L, Cohan D, Wilson ML, Maki PM. Perinatal depressive symptoms in HIV-infected versus HIV-uninfected women: a prospective study from preconception to postpartum. J Womens Health (Larchmt). 2011 Sep;20(9):1287-95. doi:10.1089/jwh.2010.2485. Epub 2011 Jul 6. PubMed PMID: 21732738; PubMed Central PMCID: PMC3168970.

14: Maki PM, Dennerstein L, Clark M, Guthrie J, LaMontagne P, Fornelli D, Little D, Henderson VW, Resnick SM. Perimenopausal use of hormone therapy is associated with enhanced memory and hippocampal function later in life. Brain Res. 2011 Mar 16;1379:232-43. doi: 10.1016/j.brainres.2010.11.030. Epub 2010 Nov 13. PubMed PMID: 21078303; PubMed Central PMCID: PMC3046212.


Pauline Maki, PhD

Professor of Psychiatry and Psychology
Director of Women’s Mental Health Research

Dr. Pauline M. Maki is a Professor in the Departments of Psychiatry and Psychology at the University of Illinois at Chicago. Dr. Maki’s research over the last 18 years has focused on women’s mental and cognitive health. She has a longstanding interest in sex differences in cognitive and psychiatric disorders. In particular, the goal of her work is to improve the lives of women by identifying risk factors and protective factors that alter their risk of cognitive decline and affective disorders. Women’s cognitive abilities, mood, and response to stress can be affected by changes in estrogen, including changes that occur during the menopausal transition, during pregnancy, and across the menstrual cycle. Much of Dr. Maki’s research focuses on how the menopausal transition and symptoms such as hot flashes affect women’s cognitive performance, brain function and response to stress. Additionally, her research investigates the efficacy and mechanism of action of interventions such as hormone therapy, soy, and other nonhormonal interventions as a means of maintaining memory performance and mood during the menopausal transition.

Dr. Maki’s research on women’s cognitive health and mood extends to the study of women and HIV. She spearheaded the incorporation of a longitudinal cognitive test battery into the Women’s Interagency HIV Study (WIHS). The WIHS is the largest longitudinal study of the natural and treated history of HIV in women. The WIHS represents the largest study of neurocognition in women with HIV to date; approximately 1,000 HIV-infected women and 600 controls participate in that longitudinal neurocognitive study. Dr. Maki is particularly interested in how sex-specific risk factors for cognitive impairment, including menopause and sex steroid hormones, affect cognition, brain function and mood in HIV-infected women. She also studies the role of drug abuse on cognition and brain function in women with HIV. In other HIV-related service activities, she serves on the Executive Committee Member and Leader of HIV and Aging Emphasis Group, Chicago Developmental Center for AIDS Research.

Dr. Maki received her Ph.D. in experimental psychology from the University of Minnesota in 1994. She received post-graduate training at the Johns Hopkins University School of Medicine in the dementias of aging and at the National Institute on Aging in neuroimaging. In 1999, she joined the Intramural Research Program of the National Institute on Aging. In 2002, she joined the faculty at the University of Illinois at Chicago. At UIC she directs the Women’s Mental Health Research Program. An active area of research in that program is the development of novel approaches to screen, assess, and treat perinatal depression and anxiety disorders. She also serves as the Senior Director of Research for the UIC Center for Research on Women & Gender and as Program Director of the UIC Building Interdisciplinary Research Careers in Women’s Health (BIRCWH). She serves as a mentor to assistant professors, postdocs, graduate students and undergraduate students.

Dr. Maki is the President of the North American Menopause Society (NAMS), a member of the NAMS Board of Trustees, Director the NAMS Mentorship Program, and the immediate past Chair of the NAMS Research Affairs Committee, and the. She has numerous publications on hormones and cognitive function, won a number of NIH awards for her research and service, serves on executive committees for several women’s health advisory boards, and is a frequent international and national speaker on women’s cognitive health.

Women, cognition, mood, stress, HIV, Alzheimer’s disease, perinatal depression and anxiety, mentorship

North American Menopause Society – President, Board of Trustees Member
BIRCWH (Building Interdisciplinary Research Careers in Women’s Health) - Program Director
International Menopause Society
National Network of Depression Centers
Women’s Interagency HIV Study - Neurocognitive Working Group
Chicago Center for AIDS Research - Special Emphasis Area Leader in HIV and Aging
Editorial Board Menopause, Member

Research Investigation of Soy and Estrogen; Women’s Interagency HIV Study

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