CONTACT INFORMATION
University of Illinois at Chicago
Department of Psychiatry
Neuropsychiatry Institute
912 W. Wood Street, Room-328
Chicago, IL 60612
Office Phone: (312) 996-6941
E-mail:
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Assistant:
Mary Winters, 312-355-5652,
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Chicago Developmental Center for AIDS Research
http://www.chicagocfar.org/
Women’s Interagency HIV Study
http://statepiaps.jhsph.edu/wihs/
KEY PUBLICATIONS
Martin, E., Gonzalez, R., Vassileva, J., and Maki, P. (in press) HIV+ men and women show different performance patterns on procedural learning tasks. Journal of Clinical and Experimental Neuropsychology.
Sunderman, E., Maki, P., & Bishop, J. (2010) A review of estrogen receptor alpha gene (ESR1) polymorphisms, mood, and cognition. Menopause. 17:874-86.
Maki, P.M., Freeman, E.W., Greendale, G.A., Henderson, V.W., Newhouse, P.A., Schmidt, P.J., Scott, N.F., Shively, C.A., & Soares, C.N. (2010) Summary of the NIA-sponsored conference on depressive symptoms and cognitive complaints in the menopausal transition. Menopause. 17:815-22.
Craig, M.C., Brammer, M., Maki, P.M., Fletcher, P.C., Dal,y E.M., Rymer J., Giampietro V., Picchioni, M., Stahl, D., Murphy, D.G. (2010) The interactive effect of acute ovarian suppression and the cholinergic system on visuospatial working memory in young women. Psychoneuroendocrinology. 35:987-1000.
Wilson, T.E., Jean-Louis, G., Schwartz, R., Golub, E.T., Cohen, M.H., Maki, P., Greenblatt, R., Massad, L.S., Robison, E., Goparaju, L., Lindau, S. (2010) HIV infection and women's sexual functioning. Journal of Acquired Immune Deficiency Syndrome. 54:360-7.
Espeland, M.A., Shumaker, S.A., Limacher, M., Rapp, S.R., Bevers, T.B., Barad, D.H., Coker, L.H., Jaramillo, S.A., Stefanick, M.L., Lane, D.S., Maki, P.M., Resnick, S.M, for the WHIMS and CoSTAR Study Groups. (2010) Relative effects of tamoxifen, raloxifene, and conjugated equine estrogens on cognition. Journal of Women’s Health. 19(3):371-9
Resnick, S.M., Espeland, M.A., An, Y., Maki, P.M., Coker, L.H., Jackson, R., Stefanick, M.L., Wallace, R., Rapp, S.R. for the Women's Health Initiative Study of Cognitive Aging Investigators. (2009) Effects of conjugated equine estrogens on cognition and affect in postmenopausal women with prior hysterectomy. Journal of Clinical Endocrinology and Metabolism. 94:4152-61.
Maki, P.M., Rubin, L.H., Fornelli, D., Drogos, L., Banuvar, S., Shulman L., & Geller, S. (2009) Effects of botanicals and combined hormone therapy on cognition in postmenopausal women. Menopause. 16:1167-77.
Legault, C., Maki, P.M., Resnick, S.M., Coker, L., Hogan, P., Bevers, T.B., Shumaker, S.A. for the Co-STAR study (2009) Effects of tamoxifen and raloxifene on memory and other cognitive abilities: Cognition in the Study of Tamoxifen and Raloxifene (Co-STAR). Journal of Clinical Oncology. 27:5144-52
Maki PM, Cohen MH, Weber K, Little DM, Fornelli D, Rubin LH, Perschler P, Gould F, and Martin E. Impairments in Memory and Hippocampal Function in HIV+ Versus HIV- Women: A Preliminary Study. Neurology. 2009. 72:1661-8.
Pauline Maki, PhD
Professor of Psychiatry and Psychology
Director of Women’s Mental Health Research
Dr. Pauline M. Maki is a Professor in the Departments of Psychiatry and Psychology at the University of Illinois at Chicago. Dr. Maki’s research over the last 12 years has focused on women’s mental and cognitive health. She has a longstanding interest in the effects of sex hormones and phytoestrogens on cognition, brain function, and psychological wellbeing in young, midlife and elderly women. Her brain imaging research led to novel insights into the neural targets of hormone therapy in postmenopausal women.
Dr. Maki received her Ph.D. in experimental psychology from the University of Minnesota in 1994. She received post-graduate training at the Johns Hopkins University School of Medicine in the dementias of aging and at the National Institute on Aging in neuroimaging. In 1999, she joined the Intramural Research Program of the National Institute on Aging, where she became a co-developer and Co-Principal Investigator in the Women’s Health Initiative Study of Cognitive Aging (WHISCA) and Cognition in the Study of Tamoxifen and Raloxifene (Co-STAR).
In 2002, she joined the faculty at the University of Illinois at Chicago, where she received funding from the National Institutes of Health to conduct randomized clinical trials comparing hormone therapy to alternative botanical therapies. Dr. Maki is a member of the North American Menopause Society (NAMS) Board of Trustees, the Chair Elect of the NAMS Research Affairs Committee, and the Director the NAMS Mentorship Program. She has numerous publications on hormones and cognitive function, won a number of NIH awards for her research and service, serves on executive committees for several women’s health advisory boards, and is a frequent international and national speaker on women’s cognitive health.
Dr. Maki serves as the Chair of the Neurocognitive Working Group of the Women’s Interagency HIV Study (WIHS). The WIHS is the largest longitudinal study of the natural and treated history of HIV in women. In this role she directs the largest study of neurocognition in women with HIV to date; approximately 1,000 HIV-infected women and 600 controls participate in that longitudinal neurocognitive study. Dr. Maki’s particular scientific interests are in the role of genetics and sex-specific risk factors for cognitive impairment, including menopause and sex steroid hormones. She is the PI on two NIH-funded neuroimaging studies examining the impact of HIV and drug use on verbal memory and related neural systems. In other HIV-related service activities, she serves on the Executive Committee Member and Leader of HIV and Aging Emphasis Group, Chicago Developmental Center for AIDS Research.
Interests:
Effects of sex hormones and phytoestrogens on cognition, brain function, and psychological wellbeing in young, midlife and elderly women. Neurocognition in Women with HIV
North American Menopause Society - Board of Trustees Member
North American Menopause Society - Chair-Elect Research Affairs Committee
North American Menopause Society - Mentorship Program, Director
North American Menopause Society - Mentorship Program, Mentor
Women’s Interagency HIV Study - Head of Neurocognitive Working Group
Women’s Interagency HIV Study - Scientific Chair Committee Member
Chicago Center for AIDS Research - Special Emphasis Area Leader in HIV and Aging
Faculty of 1000 Medicine, Member
Editorial Board Menopause, Member
Projects:
Research Investigation of Soy and Estrogen; Women’s Interagency HIV Study
