James Auta


University of Illinois at Chicago
Department of Psychiatry
Psychiatric Institute
1601 W taylor Street (M/C 912)
Chicago, IL 60608

Office Phone: (312) 355-4857
E-mail: This email address is being protected from spambots. You need JavaScript enabled to view it.



Auta J, Kadriu B, Giusti P, Costa E, Guidotti A. (2010) Anticonvulsant, anxiolytic, and non-sedating actions of imidazenil and other imidazo-benzodiazepine carboxamide derivatives. Pharmacol Biochem Behav. 95:383-389.

Kadriu B, Guidotti A, Costa E, Auta J (2009) Imidazenil, a non-sedating anticonvulsant benzodiazepine is more potent than diazepam in protecting against DFP-induced seizures and neuronal damage. Toxicology 256:164-174

Pibiri F, Kozikowski AP, Pinna G, Auta J, Kadriu B, Costa E and Guidotti A (2008): The combination of huperzine A and imidazenil is an effective strategy to prevent diisopropyl fluorophosphate toxicity in mice. PNAS 105:14169-14174

Auta J, Impagnatiello F, Kadriu B, Guidotti A, Costa E. Imidazenil: a low efficacy against at Alpha-1 but high efficacy at alpha-5 GABAA receptors fail to show anticonvulsant cross tolerance to diazepam or zolpidem. Neuropharm. 55 (2): 148-53, 2008.

Guidotti A, Auta J, Davis JM, Dong E, Grayson DR, Veldic M, Zhang X, Costa E. GABAergic Dysfunction in schizophrenia: a new treatment target on the horizon. Psychopharmacology (Berlin) 180: 191-205, 2005.

Auta J, Costa E, Davis J and Guidotti A. Imidazenil: An antagonist of the sedative but not the anticonvulsant action of diazepam. Neuropharm. 49: 425-429, 2005

Costa E, Auta J, Grayson D, Matsumoto K, Pappas DG, Zhang X and Guidotti A. GABAA receptors and Benzodiazepines: A role for dendritic resident subunit mRNAs. Neuropharm. 43: 925-937, 2002

Izzo E, Auta J, Impagnatiello F, Pesold C, Guidotti A and Costa E. Glutamic Acid Decarboxylase and Glutamate Receptor changes during tolerance and dependence to benzodiazepines. Proc. Natl. Acad. Sci. USA 98(6): 3483-3488, 2001

Auta J, Guidotti A and Costa E. Imidazenil Prevention of Alprazolam-induced acquisition deficit in Patas monkeys is devoid of tolerance. Proc. Natl. Acad. Sci. USA, 97(5): 2314-2319, 2000.

Lacor PN, Grayson DR, Auta J, Sugaya I, Costa E and Guidotti A. Reelin secretion from glutamatergic neurons in culture is independent of neurotransmitter regulation. Proc. Natl. Sci. USA 97(7):3556-3561, 2000

James Auta, PhD

Research Associate Professor

Behavioral and molecular pharmacology of nicotine and benzodiazepine tolerance and dependence, new anticonvulsant treatment strategies for organophosphate poisoning.

Imidazenil as a protective agent against nerve agents, mechanisms of cigarette smoking and schizophrenia.

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