www.psych.uic.edu

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CARE INRC publications 2016

The Center for Alcohol Research in Epigenetics (CARE) hosted its first annual retreat on March 31st, 2016. The retreat promotes alcohol research in the Chicagoland area and serves as a platform for junior researchers to present their findings in the field of alcohol use disorders. The retreat was initiated by the welcoming remarks of Dr. Anand Kumar, Head of the Department of Psychiatry at UIC, followed by inaugural remarks of Dr. Subhash Pandey, Center Director. The retreat was divided into two sessions; the first session was attended by senior staff and faculty of CARE, NIH-NIAAA Director of the Division of Neuroscience and Behavior and special guest Dr. Antonio Noronha, as well as the center’s external advisory board members which include; Dr. Harriet de Witt (University of Chicago), Dr. Dipak Sarkar (Rutgers University), Dr. Gary Wand (Johns Hopkins School of Medicine), Dr. Robert Swift (Brown University), and Dr. Lawrence Chandler (Medical University of South Carolina). In the first session, CARE faculty summarized the key findings from each research component, the overall progress of CARE, and a briefly summarized the center’s future goals. Dr. Antonio Noronha concluded the first session by addressing the Board and CARE faculty and delivering closing remarks. He appreciated the efforts of CARE alcohol researchers for making excellent progress in a very short period of time. This session was followed by a rousing presentation entitled, “Epigenetic and cellular mechanisms of stress and alcoholism” by keynote speaker, Dr. Gary Wand of Johns Hopkins Medical University. Following the talk, guests attended the retreat's poster presentation session. A total of 36 posters were submitted and presented by junior faculty and trainees from UIC, Loyola University of Chicago, and the University of Chicago. To conclude the retreat, the top three posters were recognized by a panel of judges and first, second, and third place prizes were presented to the winners by Drs. Noronha, Pandey, and Kumar. In general, the retreat was well attended and created an outstanding environment for scientific discussion towards better understanding the neurobiology of alcoholism.

 

marc atkins1.captioned

CEOP is an adjunct of CARE with the goal of providing educational opportunities and scientific knowledge about alcohol and its affects on brain structure and cognitive functioning (genes and environmental factors) to high school students, faculty, and other community sites. Dr. Marc Atkins, Professor of Psychiatry and Psychology and Director of Institute for Juvenile Research at UIC will direct the CEOP.

DATE AND LOCATION NAME TITLE

October 3, 2016
9:30am - 10:30m

Psychiatric Institute Building (SPH/PI)
1601 West Taylor Street, Room 366 Chicago, IL 60612

Hector J. Caruncho, PhD
Professor of Pharmacy
University of Saskatchewan

Lisa E. Kalynchuk, PhD
Professor of Medicine
University of Saskatchewan

“Studies on Reelin and Depression; from Bench to Bedside to Bench”

September 22, 2016
1:00pm - 2:00pm

Psychiatric Institute Building (SPH/PI)
1601 West Taylor Street, Room 366 Chicago, IL 60612

Frederic Woodward Hopf, PhD
Associate Adjunct Professor
Department of Neurology
University of California, San Francisco

“Neurocircuitry of a bad decision: to drink or not to drink”

September 12, 2016
9:30am - 10:30m

Psychiatric Institute Building (SPH/PI)
1601 West Taylor Street, Room 366 Chicago, IL 60612

Aimee Karstens
PhD Student in Clinical Psychology
Department of Psychiatry, UIC

Eleonora Gatta
Postdoctoral Research Associate
Department of Psychiatry, UIC

“The separate and interactive associations of urban trauma and depression on brain structure”

“The long-term outcome of perinatal stress: molecular basis of emotional behavior”

August 25, 2016
1:00pm - 2:00pm

Psychiatric Institute Building (SPH/PI)
1601 West Taylor Street, Room 366 Chicago, IL 60612

Rajita Sinha, PhD
Foundations Fund Chair in Psychiatry
Professor of Psychiatry, Director, Yale Interdisciplinary Stress Center
Department of Psychiatry, Yale University School of Medicine

“Understanding alcohol craving and relapse to improve treatment outcome and recovery”

August 8, 2016
9:30am - 10:30m

Psychiatric Institute Building (SPH/PI)
1601 West Taylor Street, Room 366 Chicago, IL 60612

Evan Kyzar
MD/PhD Student, MSTP Program
Department of Psychiatry, UIC


Kerry Kinney
Graduate Student
Department of Psychiatry, UIC

“Decreased histone demethylases in the adult amygdala alter chromatin dynamics and anxiety-like behavior following adolescent alcohol.”

“Examining the relationship between self-reported emotion regulation and the neurophysiology of emotion regulation”

July 28, 2016
1:00pm - 2:00pm

Psychiatric Institute Building (SPH/PI)
1601 West Taylor Street, Room 366 Chicago, IL 60612

A. Leslie Morrow, PhD
John Andrews Distinguished Professor
Departments of Psychiatry and Pharmacology
Associate Director, Bowles Center for Alcohol Studies
University of North Carolina School of Medicine, Chapel Hill

“Ethanol regulation of GABA-A receptors involves epigenetic mechanisms”

July 15, 2016
1:00pm - 2:00pm

Psychiatric Institute Building (SPH/PI)
1601 West Taylor Street, Room 366 Chicago, IL 60612

Cindy Ehlers, PhD
Professor, Department of Molecular and Cellular Neuroscience
and Department of Molecular and Experimental Medicine
The Scripps Research Institute

“Adolescent alcohol use causes and consequences”

July 11, 2016
9:30am - 10:30am

Psychiatric Institute Building (SPH/PI)
1601 West Taylor Street, Room 366 Chicago, IL 60612

Bertha Vandergrift
Graduate Student
Department of Physiology & Biophysics, UIC

Katie Bessette
Graduate Student
Department of Psychiatry, UIC

“High estrogen states increase ethanol and dopamine effects in ventral tegmental area neurons from free-cycling and ovariectomized female mice.”

“Cognitive vulnerabilities for depression and alcohol use.”

June 20, 2016
1:00pm - 2:00pm

Psychiatric Institute Building (SPH/PI)
1601 West Taylor Street, Room 366 Chicago, IL 60612

Prof. Gurcharan Kaur, PhD
Dean of Faculty of Life Sciences
Prof-in-Charge, Placement Department
Department of Biotechnology
Guru Nanak Dev University, India

“Molecular insights in the multifunctional neuroprotective activities from Indian medicinal plants”

June 13, 2016
9:30am - 10:30am

Psychiatric Institute Building (SPH/PI)
1601 West Taylor Street, Room 366 Chicago, IL 60612

Laura Segura
PhD candidate
Department of Psychiatry, UIC

Nathan Wray
PhD Candidate
Department of Physiology and Biophysics, UIC

“Characterization of a novel mouse model of post-traumatic headache.”

“The role of astrocytes in antidepressant actions of ketamine.”

May 26, 2016
1:00pm - 2:00pm

Psychiatric Institute Building (SPH/PI)
1601 West Taylor Street, Room 366 Chicago, IL 60612

Dorit Ron, PhD
Professor of Neurology & Director of Alcohol Research Center
University of California, San Francisco

“Striatal signaling and alcohol abuse disorders”

May 9, 2016
9:30am - 10:30am

Psychiatric Institute Building (SPH/PI)
1601 West Taylor Street, Room 366 Chicago, IL 60612

Emma Childs, PhD
Visiting Associate Professor
Department of Psychiatry, UIC

Greg Bristow, DPhil
Postdoctoral Research Associate
College of Pharmacy, UIC

“Conditioned place preference in humans using virtual environments”

“Prenatal stress produces long-term effects on RNA editing and behavior that are eliminated by clozapine”

April 28, 2016
1:00pm - 2:00pm

Psychiatric Institute Building (SPH/PI)
1601 West Taylor Street, Room 366 Chicago, IL 60612

Dr. K. Luan Phan, MD
Professor and Director, Mood and Anxiety Disorders Research Program
Department of Psychiatry, UIC
Staff Psychiatrist, Jesse Brown VA Medical Center

“Imaging Stress in Humans”

April 11, 2016
9:30am - 10:30am

Psychiatric Institute Building (SPH/PI)
1601 West Taylor Street, Room 366 Chicago, IL 60612

Ritabrata Banerjee, PhD
Postdoctoral Research Associate
Department of Psychiatry, UIC

Lisanne Jenkins, PhD
Postdoctoral Research Fellow
Department of Psychiatry, UIC

“Role of CB1 receptor signaling in alcohol intake”

“Reduced connectivity of the cognitive control neural network at rest in individuals who begin drinking alcohol prior to age 18”

March 14, 2016
9:30am -10:30am

Psychiatric Institute Building (SPH/PI)
1601 West Taylor Street, Room 366 Chicago, IL 60612

Ana Vicente-Sanchez, PhD
Postdoctoral Research Associate
Department of Psychiatry, UIC

 

Antonia Savarese
PhD Candidate, Neuroscience Program
Department of Psychiatry, UIC

“Biased agonism at the delta opioid receptor”

 

“Characterization of behavioral phenotypes and gene expression changes related to alcohol use disorders in mice deficient in the Lim-only protein, LMO3”

February 15, 2016
12:00pm - 1:00pm

Psychiatric Institute Building (SPH/PI)
1601 West Taylor Street, Room 366 Chicago, IL 60612

Ketan Marballi, PhD
Postdoctoral Fellow
Waggoner Center for Alcohol Addiction Research
University of Texas at Austin

“Translational studies in psychiatric and addiction disorders”

February 8, 2016
9:30am -10:30am

Psychiatric Institute Building (SPH/PI)
1601 West Taylor Street, Room 366 Chicago, IL 60612

Rosalba Satta, PhD
Postdoctoral Research Associate
Department of Psychiatry, UIC

“Activation of estrogen receptor (ER) b in the nucleus accumbens enhances cocaine conditioned place preference”

 


January 28, 2016
1:00pm - 2:00pm

Psychiatric Institute Building (SPH/PI)
1601 West Taylor Street, Room 366 Chicago, IL 60612

Michael A. Collins, PhD
Professor, Department of Molecular Pharmacology & Therapeutics
Loyola University Chicago Stritch School of Medicine

"Alcohol and brain neurodamage: key roles for PARP and PLA2"

January 11, 2016
9:30am - 10:30am

Psychiatric Institute Building (SPH/PI)
1601 West Taylor Street, Room 366 Chicago, IL 60612

Jeff Schappi
PhD Candidate
Department of Psychiatry, UIC




Harinder Singh, PhD
Post-doctorate Research Associate
Department of Physiology & Biophysics, UIC

“Modified lipid raft anchoring of the G protein, Gas subsequent to chronic antidepressant treatment, is independent of monoamine transporters but requires type 6 adenylyl cyclase (AC6).”

 

"HDAC6 inhibition induced a-tubulin acetylation translocates Gas out of lipid-rafts: a novel mechanism for antidepressant action."


December 14, 2015
9:30am -10:30am

Psychiatric Institute Building (SPH/PI)
1601 West Taylor Street, Room 366 Chicago, IL 60612

 

Andrew Widmer, MD/PhD
Student, MSTP Program
Department of Psychiatry, UIC

Chang You, PhD
Post-doctorate Research Associate Department of Biophysics and Physiology, UIC

“Inhibitory function in the Fragile X olfactory cortex.”

 

"GABA Hyposensitivity in Dopamine Neurons of the Ventral Tegmental Area after Chronic Alcohol Exposure: an Epigenetic Regulation Mechanism".

November 9, 2015
9:30am -10:30am

Psychiatric Institute Building (SPH/PI)
1601 West Taylor Street, Room 366 Chicago, IL 60612

Joseph Lutz, PhD
Postdoctoral Research Associate
Department of Psychiatry, UIC

Natania Crane, MA
PhD Candidate in Clinical Psychology
Clinical Psychology Division, UIC

“Identifying alcohol response phenotypes among a sample of heavy drinkers”

 

“Neuropsychological, Affective, and Psychosocial Correlates of Adolescent Substance Use: Preliminary Data”

Oct 22, 2015

Psychiatric Institute Building (SPH/PI)
1601 West Taylor Street, Room 366 Chicago, IL 60612

 

Kylee Veazey, PhD
Graduate Research Assistant

Veterinary Physiology and Pharmacology
Reproductive Sciences Lab
Texas A&M University

"An epigenetic basis to the etiology of Fetal Alcohol Spectrum Disorders"

Oct 12, 2015
9:30am -10:30am

Psychiatric Institute Building (SPH/PI)
1601 West Taylor Street, Room 366 Chicago, IL 60612

Stephanie Forkel, PhD
Postdoctoral Researcher Clinical Neuroimaging
President of Clinical Neuroanatomy Society

Department Neuroimaging
King’s College London

“Towards a new connectional anatomy of language”

October 7, 2015
1:00pm - 2:00pm

School of Public Health/Psychiatric Institute
Auditorium, Room 109
1601 West Taylor Street Chicago, IL 60612

Psychiatry Grand Rounds: Adron Harris, PhD
Professor and Director Waggoner Center for Alcohol & Addiction Research
University of Texas at Austin

"Alcohol and the Brain: Can Genomics Lead to New Therapies?"

Sep 28, 2015
1.00pm- 2.00pm

College of Medicine, Research Building, Moss Auditorium, Room 1020, 909 S. Wolcott

George F. Koob, PhD
Director, National Institute on Alcohol Abuse and Alcoholism

National Institutes of Health

“How does science inform diagnosis, prevention, treatment of alcoholism: New Priorities at NIAAA”

Sep 14, 2015
9.30am - 10.30am

Psychiatric Institute Building (SPH/PI)
1601 West Taylor Street, Room 366 Chicago, IL 60612

Hu Chen, PhD
Research Assistant Professor, Department of Psychiatry

University of Illinois at Chicago

"Repeated Binge Drinking Increases Perineuronal Nets in the Insular Cortex”

Aug 27, 2015
1:00pm - 2:00pm

Psychiatric Institute Building (SPH/PI)
1601 West Taylor Street, Room 366
Chicago, IL 60612

Alessandro Guidotti, PhD
Professor and Scientific Director, Psychiatric Institute

Department of Psychiatry, University of Illinois at Chicago

“Early life stress and brain epigenetic imprinting”

August 10, 2015
9:30am -10:30am

 

Psychiatric Institute Building (SPH/PI)
1601 West Taylor Street, Room 366 Chicago, IL 60612

Elisa R. Hilderbrand
PhD Student
Neuroscience Program
Department of Psychiatry, University of Illinois at Chicago

Tiffani Berkel
MD/PhD Student
Neuroscience and MSTP Program
Department of Psychiatry, University of Illinois at Chicago

“Ethanol and the Female Brain: Estrogen as a regulator of Ethanol Reward and Binge Drinking Behavior”

 

“Potential Histone Methylation Mechanisms in Anxiety and Alcoholism”

 

July 6, 2015
9:30am - 10:30am

Psychiatric Institute Building (SPH/PI)
1601 West Taylor Street, Room 366 Chicago, IL 60612

Dadasaheb M. Kokare, PhD
Visiting Research Scholar
Center for Alcohol Research in Epigenetics (CARE)
University of Illinois at Chicago

 

“Role of Alpha-MSH-MC 4 Receptor Systems in Alcoholism"

June 8, 2015

 

Psychiatric Institute Building (SPH/PI)
1601 West Taylor Street, Room 366 Chicago, IL 60612

Fulton T. Crews, PhD
John Andrews Distinguished Professor
Professor of Pharmacology and Psychiatry
Director, Bowles Center for Alcohol Studies School of Medicine

University of North Carolina at Chapel Hill

“Neuroimmune signaling through HMGB1-TLR Receptors Contributes to Alcoholic Neuropathology”

May 11, 2015

Psychiatric Institute Building (SPH/PI)
1601 West Taylor Street, Room 366 Chicago, IL 60612

Bradley Heit
PhD Student

“Ex-vivo Study of Neuroprotective   Effects of Physical Exercise”

May 11, 2015

Psychiatric Institute Building (SPH/PI)
1601 West Taylor Street, Room 366 Chicago, IL 60612

Harish Krishnan, PhD
Research Associate
Center for Alcohol Research in Epigenetics

Department of Psychiatry
University of Illinois at Chicago

“Chromatin Remodeling and Rapid Tolerance to Anxiolytic Effects of Alcohol”

May 6, 2015

School of Public Health/Psychiatric Institute
Auditorium, Room 109 1601 West Taylor Street Chicago, IL 60612

 

Psychiatry Grand Rounds: Adolf Pfefferbaum, MD/PhD
Senior Program Director & Distinguished Scientist
Neuroscience Program

Center for Health Sciences
SRI International

“Alcohol and the brain: An In-vivo   Neuroimaging Perspective”

April 27, 2015

Psychiatric Institute Building (SPH/PI)
1601 West Taylor Street, Room 366 Chicago, IL 60612

Subhash C. Pandey, PhD
Professor and Director
Center for Alcohol Research in Epigenetics

Department of Psychiatry
University of Illinois at Chicago

“An Overview of Current and Future Research of UIC Alcohol Research Center”

April 13, 2015
9:30am - 10:30am

Psychiatric Institute Building (SPH/PI)
1601 West Taylor Street, Room 366 Chicago, IL 60612

Evan Kyzar
MD/PhD Student
Neuroscience and MSTP Program

Department of Psychiatry
University of Illinois at Chicago

“Histone Methylation Mechanisms during Adolescent Binge Ethanol Exposure”

Capture3CARE will provide resources and a scientifically enriched environment for training opportunities, coordinated by Dr. Mark Rasenick, dept. of Biophysics and Physiology and Psychiatry UIC.

CARE investigators are currently working with several MD/PhD students from MSTP program of UIC, as well as PhD students from Neuroscience Graduate Program of UIC.

http://chicago.medicine.uic.edu/mstp (MSTP)

http://www.uic.edu/depts/neurosci/program.htm  (Neuroscience Graduate Program of UIC.)

 

 

 

 

 

 

 

                                                                                                                                                                                                                                               

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