For information on Cellular Manifestations of Aging in Rat Olfactory Cortext, please visit:

http://www.psych.uic.edu/research/rat_olfactory_cortex.htm

For information on the Neurobiology of of Aging in the Mouse Olfactory System, please visit:

http://www.psych.uic.edu/research/mouse_olfactory.htm

For inormation on Benzodiazepines, Long-term Potentation, and Memory, please visit:

http://www.psych.uic.edu/research/longterm_potentiation.htm

Research Interests:

• 1981 B.S., Psychology, University of Illinois at Urbana-Champaign
• 1987 Ph.D., Psychobiology, University of California, Irvine
• 1986-1988 Postgraduate Researcher, Center for the Neurobiology of Learning and Memory, University of California, Irvine
• 1987 Donald B. Lindsley Prize in Behavioral Neuroscience from the Society for Neuroscience
• 1988-1993 Assistant Research Neurobiologist, Center for the Neurobiology of Learning and Memory, University of California, Irvine
• 1993-1997 Associate Research Neurobiologist, Center for the Neurobiology of Learning and Memory, University of California, Irvine
• 1997-Present Assistant Professor of Physiology in Psychiatry, Psychiatric Institute, Department of Psychiatry, University of Illinois at Chicago, Chicago, IL

• Larson, J., Lieu, T., Petchpradub, V., LeDuc, B., Ngo, H., Rogers, G., & Lynch, G. Facilitation of olfactory learning by a modulator of AMPA receptors. Journal of Neuroscience, 15 (1995) 8023-8030.
• Sirvio, J., Larson, J., Quach, C.N., Rogers, G., & Lynch, G. Effects of pharmacologically facilitating glutamatergic transmission in the trisynaptic intrahippocampal circuit. Neuroscience, 74 (1996) 1025-1035.
• Larson, J., Quach, C.N., LeDuc, B.Q., Nguyen, A., Rogers, G.A., & Lynch, G. Effects of an AMPA receptor modulator on methamphetamine-induced hyperactivity activity in rats. Brain Research, 738 (1996) 353-356.
• Hoffman, K.B., Larson, J., Bahr, B.A., & Lynch. G. Activation of NMDA receptors stimulates extracellular proteolysis of cell adhesion molecules in hippocampus. Brain Research, 811 (1998) 152-155.
• Niittykoski, M., Ruotsalainen, S., Haapalinna, A., Larson, J., & Sirvio, J. Activation of muscarinic M3-like receptors and -adrenoceptors, but not M2-like muscarinic receptors or -adrenoceptors, directly modulates cortico-striatal neurotransmission in vitro. Neuroscience, 90 (1999) 95-105.
• Larson, J., Lynch, G., Games, D., & Seubert, P. Alterations in synaptic transmission and long-term potentiation in hippocampal slices from young and aged PDAPP mice. Brain Research, 840 (1999) 23-35.

• "Electrophysiological Correlates of Neuropathology in Transgenic Mouse Models of Alzheimer's Disease", 33rd Winter Conference on Brain Research, Breckinridge, CO, January 25, 2000