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Dr. Goldman
is an Associate Professor of Psychiatry at the Pritzker University
School of Medicine, University of Chicago and a lecturer at
the University of Illinois at Chicago. He was born and
raised in Phoenix, Arizona, completed his Bachelors Degree,
summa cum laude, in Chemistry at Occidental College in
1975; his Medical Degree at University of Pennsylvania in 1980,
his residency in psychiatry at University of Chicago in 1984,
and a NIMH-sponsored neuroendocrine fellowship in 1986. He has
been Board Certified by the American Board of Psychiatry and
Neurology since 1985. He has received other fellowships from
the National Science Foundation and National Fund for Medical
Education, and was recognized as the Mentor of the Year by the
Illinois Psychiatric Association. He has published in the New
England Journal of Medicine, The Lancet, basic science journals
including Brain Research and JCI, as well as the major journals
in Psychiatry. Since 1989 he has been a research psychiatrist
at the Illinois State Psychiatric Institute and is now the Program
Director of the University of Chicago research program at the
Psychiatric Institute. Additional information about Dr. Goldman's
current clinical and research activities is available
on his University
of Chicago Web Page.
Dr. Goldman's
research interests have been to improve the treatment and clarify
the mechanisms of the life threatening water imbalance
that afflicts about 3 to 5 % of chronic schizophrenic patients.
More recently the focus has been on clarifying the relationship
between these patients' (i.e. hyponatremic polydipsic schizophrenics)
enhanced activity of the antidiuretic hormone, arginine vasopressin,
and their underlying neuropsychiatric disorder. Specifically,
he is now testing the hypothesis that their neuropsychiatric
disorder is caused by an imagable hippocampal lesion which
disrupts the constraint of their neuroendocrine,
behavioral, affective and cognitive responses to psychological
stress. His research is currently funded by the NIH (R01MH56525),
an investigator initiated grant with Eli Lilly, the University
of Chicago Brain Research Foundation, and the University of
Illinois sub-contract with the University of Chicago.
A description
of Dr. Goldman's currently active clinical protocols, and information
about enrolling in these studies is provided here.
A summary
of the previous work of his lab, its current (5/2000) and future
direction (particularly fMRI) is also available. The references
included with this summary identify many of this group's contributions,
as well as those that have influenced its work. Additional information
can be obtained by contacting Dr.
Goldman or his secretary.
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