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Clinical Profile of an Atypical Antipsychotic: Risperidone
John A. Davis and Nancy Chen

Table 1. Differences between Risperidone 6 mg/day and Risperidone
10-16 mg on the 30 PANSS items and total score

PANSS Items
t253
P-value
Delusions
-0.95
0.342
Conceptual Disorganisation
-0.74
0.461
Hallucinatory Behaviour
-2.33
0.021
Excitement
-2.13
0.034
Grandiosity
-1.58
0.114
Suspiciousness/Persecution
-0.78
0.438
Hostility
-0.94
0.346
Blunted Affect
-1.82
0.069
Emotional Withdrawal
-0.68
0.495
Poor Rapport
-0.98
0.329
Passive/Apathetic Soc Withdraw
-0.55
0.580
Difficulty in Abstract Thinkng
-1.26
0.208
Lack of Spont & Flow of Conver
-0.07
0.944
Stereotyped Thinking
-1.23
0.221
Somatic Concern
-1.40
0.164
Anxiety
-2.19
0.029
Guilt Feelings
-1.22
0.222
Tension
-2.84
0.005
Mannerisms and Posturing
-1.92
0.056
Depression
-1.16
0.246
Motor Retardation
-0.21
0.836
Uncooperativeness
-1.79
0.075
Unusual Thought Content
-1.88
0.061
Disorientation
-1.45
0.148
Poor Attention
-1.24
0.215
Lack of Judgement and Insight
0.02
0.987
Disturbance of Volition
-0.70
0.485
Poor Impulse Control
-2.33
0.020
Preoccupation
-1.87
0.063
Active Social Avoidance
-1.75
0.081
Negative Symptoms
-1.20
0.230
Positive Symptoms
-1.85
0.066
Disorganized Thoughts
-1.80
0.073
Impulsivity/ Hostility
-2.34
0.020
Anxiety/ Depression
-2.51
0.013
PANSS Total
-2.15
0.032

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