Dr. Cook directs the Laboratory of Developmental Neuroscience. The Laboratory of Developmental Neuroscience is engaged in clinical and translational research in child onset neuropsychiatric disorders, including autism, obsessive-compulsive disorder, attention deficit hyperactivity disorder, bipolar mood disorder, and stuttering. Current areas of emphasis are molecular genetic, clinical pharmacologic, and pharmacogenetic studies.

Representative Publications

Weiss, L.A., Abney, M., Cook, E.H. , Ober, C.: Sex-specific genetic architecture of whole blood serotonin levels. American Journal of Human Genetics 2005,76:33-41.

Owley, T., Walton, L., Salt, J.,Guter, S.J., Winnega, M., Leventhal, B.L., Cook, E.H. : An open label trial of escitalopram in pervasive developmental disorders. Journal of the American Academy of Child and Adolescent Psychiatry 2005,44:343-348.

Stein, M.A., Waldman, I.D., Sarampote, C.S., Seymour, K.E., Robb, A.S., Conlon, C., Kim, S-J., Cook, E.H. : Dopamine transporter genotype predicts methylphenidate dose-response in children with ADHD. Neuropsychopharmacology 2005,30:1374-1382.

Hellings, J.A., Weckbaugh, M., Nickel, E.J., Cain, S.E., Zarcone, J.R., Reese, R.M., Hall, S., Ermer, D.J., Tsai, L.Y., Schroeder, S.R., Cook, E.H. : A double-blind, placebo-controlled study of valproate for aggression in youth with pervasive developmental disorders. Journal of Child and Adolescent Psychopharmacology 2005,15:682-692.

Kim, Y.S., Leventhal, B.L., Kim, S-J., Kim, B-N., Cheon, K-A, Yoo, H-J., Kim, S-J., Badner, J., Cook, E.H. : Family-based association study of DAT1 and DRD4 polymorphisms in Korean children with ADHD. Neuroscience Letters 2005,390:176-181.

Devlin, B., Cook, E.H. , Coon, H., Dawson, G., Grigorenko, E.L., McMahon, W., Minshew, N., Pauls, D., Smith, M., Spence, M.A., Rodier, P.M., Stodgell, C., the CPEA Genetics Network, Schellenberg, G.D.: Autism and the serotonin transporter: the long and short of it. Molecular Psychiatry 2005,10:1110-1116.

Geller, B., Tillman, R., Badner, J.A., Cook, E.H. : Are the arginine vasopressin V1a receptor microsatellites related to hypersexuality in children with a prepubertal and early adolescent bipolar disorder phenotype? Bipolar Disorders 2005,7:610-616.

Veenstra-VanderWeele, J., Qaadir, A., Palmer, A.A., Cook, E.H. , de Wit, H.: Association between the casein kinase 1 epsilon gene region and subjective response to D -amphetamine. Neuropsychopharmacology published online in advance of print.

Brune, C.W., Kim, S-J., Salt, J., Leventhal, B.L., Lord, C., Cook, E.H. : 5-HTTLPR genotype-specific phenotype in children and adolescents with autism. American Journal of Psychiatry in press.

Dickel, D.E., Veenstra-VanderWeele, J., Cox, N.J., Wu, X., Fischer, D.J., Van Etten-Lee, M., Himle, J.A., Leventhal, B.L., Cook, E.H. , Hanna, G.L.: Association testing of the positional and functional candidate gene SLC1A1 in early-onset obsessive-compulsive disorder. Archives of General Psychiatry in press.

Owley, T., Guter, S., Grieve, A., Walton, L., Salt, J., Arroyo, N., Leventhal, B.L., Cook, E.H. Jr. : Memantine in the treatment of cognitive and memory dysfunction in autism spectrum disorders. Journal of Child and Adolescent Psychopharmacology in press.