Department of Psychiatry
University of Illinois at Chicago
Room No. 508,
1601 West Taylor,
Chicago, IL 60612
Office Phone:312-413-4570
E-mail: This email address is being protected from spambots. You need JavaScript enabled to view it.
Assistant Name: Timothy Ryan
Office Phone:312-413-4619
E-mail: This email address is being protected from spambots. You need JavaScript enabled to view it.

Leucht S, Cipriani A, Spineli L, Mavridis D, Orey D, Richter F, Samara M, Barbui C, Engel RR, Geddes JR, Kissling W, Stapf MP, Lässig B, Salanti G, Davis JM. Comparative efficacy and tolerability of 15 antipsychotic drugs in schizophrenia: a multiple-treatments meta-analysis. Lancet. 2013 Sep 14;382(9896):951-62.

Klein, Donald F. and Davis, John M.: Diagnosis and Drug Treatment of Psychiatric Disorders. Williams and Wilkins, Baltimore, 1969

Ramsden CE, Zamora D, Leelarthaepin B, Majchrzak-Hong SF, Faurot KR, Suchindran CM, Ringel A, Davis JM, Hibbeln JR. Use of dietary linoleic acid for secondary prevention of coronary heart disease and death: Evaluation of recovered data from the Sydney Diet Heart Study and updated meta-analysis. 5 February 2013. BMJ 346:e8707.

Davis, J.M. Overview: Maintenance therapy in psychiatry: I. Schizophrenia. Amer. J. Psychiatry 132(12):1237-1245, 1975.

Ramsden CE, Hibbeln JR, Majchrzak SF, Davis JM. n-6 fatty acid specific and mixed polyunsaturated dietary interventions have different effects on CHD risk: a meta-analysis of randomized controlled trials. British Journal of Nutrition 2010; 104(11), 1586-600.

Hibbeln JR, Davis JM, Steer C, Emmett P, Rogers I, Williams C, Golding J. Maternal seafood consumption in pregnancy and neurodevelopment outcomes in childhood (ALSPAC study): an observational cohort study. Lancet 2007; 369: 578-85.

Leucht S, Corves C, Arbter D, Engel RR, Chunbo L, Davis JM. Second-generation versus first-generation antipsychotic drugs for schizophrenia: a meta-analysis. Lancet; 2008;373(9657):31-41.

Janowsky, D.S., El-Yousef, M.K., Davis, J.M., and Sekerke, H.J. A cholinergic-adrenergic hypothesis of mania and depression. Lancet 2(778):632-635, September 23, 1972.

Javaid, J.I., Fischman, M., Schuster, C.R., Dekirmenjian, H., and Davis, J.M. Cocaine plasma concentration: relation to physiological and subjective effects in humans. Science 202:227-228, 1978.

Bunney, W.E., Jr., and Davis, J.M. Norepinephrine in depressive reactions. Arch. Gen. Psychiat. 13(6):483-494, 1965.

Tamminga CA, Davis JM. (1978) Schizophrenic symptoms improve with apomorphine. Science 200:567-568.

John M. Davis, MD

Professor of Psychiatry and Research Professor of Medicine

Dr. Davis is interested in the biologic basis of major mental illness and its treatment with medication. He and his colleagues introduced the paradigm to psychiatry that major mental illness may be caused by biochemical abnormalities. His group was among the first to do studies on the pharmacodynamics and pharmacokinetics of psychotropic drugs. His educational film to teach the recognition of certain side effects to physicians won a Telly award, the equivalent of an Academy Award for education industry films. He was among the first several physicians to introduce meta-analysis as a tool to pool scientific data.

He is interested in nutrition’s effect on mental and physical health, including work on how a mother’s diet during pregnancy influence a child’s intellectual capacity and mental health. The Economist wrote a cover story on this research, the illustration to which can be seen below:
As a result of this work, the FDA’s revised its guidelines for diet of during pregnancy and the US Government’s changed its recommendations on nutrition. Dr. Davis is also interested in the role of nutrition in preventing heart attacks and strokes.


Clinical trials, meta-analysis, biochemical and epigenetic basis of mental illness, child development, obesity, the role of nutrition in mental illness, heart attacks and strokes.


The ALSPAC longitudinal study of children of the 1990s, the clinical trials program of The Stanley Medical Research Institute, a collaborative US and China investigation into the prodrome of schizophrenia.


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