University of Illinois at Chicago
Department of Psychiatry
1601 W Taylor Street , (M/C 912)
Chicago, IL 60612

Office Phone: (312) 996-5779
E-mail: This email address is being protected from spambots. You need JavaScript enabled to view it.

This email address is being protected from spambots. You need JavaScript enabled to view it. 


Lamar, M., Zhou, X.J., Charlton, R., Dean, D., Little, D. & Deoni, S.C.L. (2013). in vivo quantification of white matter microstructure in normal and pathological aging. American Journal of Geriatric Psychiatry. doi: 10.1016/j.jagp.2013.08.001.

Lamar, M., Charlton, R., Ajilore, O., Zhang, A., Yang, S., Rhodes, E., Barrick, T. & Kumar, A. (2013). Prefrontal vulnerabilities and whole brain connectivity in aging and depression: Lessons from translational tasks. Neuropsychologia, 51, 1463-1470.

Lamar, M., Charlton, R., Zhang, A. & Kumar, A. (2012) Differential associations between types of verbal memory and prefrontal brain structure in late life depression.Neuropsychologia, 50, 1823-1829.

Lamar, M., Cutter, W., Tang, C., Rubia, K., Brammer, M., Daly, E., & Murphy, D. (2012) Acute tryptophan depletion promotes an anterior-posterior fMRI activation shift in older adults during set switching. Human Brain Mapping. doi: 10.1002/hbm.22187

Lamar, M., Dannhauser, T.M., Walker, Z., Rodda, J.E., Cutinha, D.J. & Shergill, S.S. (2011). Subjective memory complaints with and without objective memory impairment: The impact of leukoaraiosis on cognitive phenotypes.Journal of the International Neuropsychological Society, 17, 1104-1112.

Lamar, M., Charlton, R.A., Morris, R.G. & Markus, H.S. (2010). The impact of subcortical white matter disease and executive functioning on depressive symptomatology in normal aging.American Journal of Geriatric Psychiatry, 18, 634-642.

Lamar, M., Price, C.C., Giovannetti, T., Swenson, R. & Libon, D.J. (2010). The dysexecutive syndrome associated with subcortical white matter disease and dementia. Behavioral Neurology, 22, 53-62.

Lamar, M., Goldstein, F., Libon, D.J., Ashley, A.V., Lah, J.J. & Levey, A.I. (2010). The impact of vascular comorbidity on abstract reasoning and concept formation in Alzheimer’s disease. Journal of the International Neuropsychological Society, 16(1), 77-83.

Lamar, M., Catani, M., Price, C.C., Heilman, K.M. & Libon, D.J. (2008). The impact of region specific leukoaraiosis on working memory deficits.Neuropsychologia, 46(10), 2597-2601.

Melissa Lamar, PhD



Dr. Lamar has a long-standing interest in the neurobiological mechanisms underlying cognitive and affective dysfunction in normal and pathological aging – with a particular emphasis on vascular aging.

Dr. Lamar received her Ph.D. in Clinical Neuropsychology from Drexel University in Philadelphia before joining the Cognition Section of the Baltimore Longitudinal Study on Aging within the intramural program of the National Institute on Aging. There through her Scientific Director’s Training Award in Research, Dr. Lamar studied the functional implications for age-related structural vulnerabilities within the prefrontal cortex of healthy older adults. It was during her time at the Institute of Psychiatry, King’s College London that Dr. Lamar began to focus more exclusively on the impact of vascular risk factors like hypertension and diabetes on brain aging, incorporating various structural MRI techniques into her work.

Since coming to UIC, Dr. Lamar has secured federal funding through the National Institutes of Health to find modifiable biomarkers of vascular risk in brain aging, quantify vascular co-morbidities across ethnically diverse populations and implement novel neuroimaging techniques for a better determination of the impact of aging and vascular risk on brain structure and function. Dr. Lamar focuses on experimental paradigms from both non-human primate lesion studies and human neuroimaging studies to strengthen the neuroanatomical accuracy of her work. Combining these tools with the Boston Process Approach to Cognitive Neuropsychology, Dr. Lamar is able to detect subtle alterations in behavior and pin-point their roots in brain.

In addition to her research activities, Dr. Lamar is the Director of Cognitive Aging and Vascular Health in the Memory and Wellness Clinic operated within the Departments of Psychiatry and Neurology. She also serves as a licensed member of staff within the Department of Psychiatry’s Neuropsychology Service.


Dr. Lamar’s research at UIC centers on the impact of vascular risk factors on brain structure and function in normal and pathological aging with an emphasis on minority health disparities.


VITAL: Vascular Integrity To Advance Longevity
The VITAL Studies look at the impact of vascular risk factors on brain aging across various populations with the goal of identifying modifiable aspects of disease at the individual and community level.

MultiCenter Repository for Digitization of the Clock Drawing Test
With Lahey Clinic in Boston, MA and Massachusetts Institute of Technology, we are using digital technology to enable new insights into motor programing and the underlying neuroanatomy involved in these processes.

To volunteer or learn more about our work, call 312-996-2677 or email This email address is being protected from spambots. You need JavaScript enabled to view it.

Interested students may also visit http://tigger.uic.edu/htbin/codewrap/bin/orgs/ura/cgi-bin/search.php?searchterm=lamar&searchtype=&college_search=


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