www.psych.uic.edu

CARE Seminar Series

DATE NAME TITLE

April 27th, 2015

Subhash C. Pandey, PhD

Professor and Director

Center for Alcohol Research in Epigenetics

Department of Psychiatry

University of Illinois at Chicago

 

“An Overview of Current and Future Research of UIC Alcohol Research Center”

May 6th, 2015

Dr. Adolf Pfefferbaum, M.D.

Senior Program Director & Distinguished Scientist

Neuroscience Program

Center for Health Sciences

SRI International

 

“Alcohol and the brain: An In-vivo   Neuroimaging Perspective”

May 11th, 2015

Harish Krishnan, PhD

Research Associate

Center for Alcohol Research in Epigenetics

Department of Psychiatry

University of Illinois at Chicago

 

“Chromatin Remodeling and Rapid Tolerance to Anxiolytic Effects of Alcohol”

May 11th, 2015

Bradley Heit

PhD Student

 

“Ex-vivo Study of Neuroprotective   Effects of Physical Exercise”

June 8th, 2015

Dr. Fulton T. Crews

John Andrews Distinguished Professor

Professor of Pharmacology and Psychiatry

Director, Bowles Center for Alcohol Studies

School of Medicine

University of North Carolina at Chapel Hill

 

“Neuroimmune signaling through HMGB1-TLR Receptors Contributes to

Alcoholic Neuropathology”

Community Outreach Program (CEOP)

capture4CEOP is an adjunct of CARE with the goal of providing educational opportunities and scientific knowledge about alcohol and its affects on brain structure and cognitive functioning (genes and environmental factors) to high school students, faculty, and other community sites. Dr. Marc Atkins, Professor of Psychiatry and Psychology and Director of Institute for Juvenile Research at UIC will direct the CEOP.

Cores

CARE Cores include:

Dr. Dennis GreysonAdministrative core: Director, Dr. Subhash Pandey Dept. of Psychiatry, UIC

Scientific Director, Dr. Alessandro Guidotti Dept. of Psychiatry, UIC.

capture3Epigenetics core: PI, Dr. Dennis Grayson, Dept. of Psychiatry, UIC.

The focus of the Epigenetics Core is on determining genome-wide changes in transcription and
epigenetic marks in response to chronic alcohol administration and withdrawal from chronic
alcohol exposure.  We will perform RNA-seq and ChIP-seq studies in cooperation with the CARE Research Projects to obtain novel information regarding genome-wide changes in gene expression and histone modifications in several brain areas important in the alcohol addiction process. Researchers from the Chicago (UIC) and Urbana-Champaign (UIUC) campuses of the University of Illinois will provide a platform for the identification and analysis of gene expression affected by chronic ethanol exposure in multiple brain regions. The different treatment paradigms and molecular biology will be performed at UIC (directed by Dr. Dennis R. Grayson). Isolated RNA and immune-precipitated DNA will be sent to UIUC for sequencing at the DNA Services Facility (directed by Dr. Alvaro Hernandez).
Bioinformatic data analysis will be performed at the High-Performance Biological Computing Roy J. Carver Biotechnology Center and Institute for Genomic Biology (directed by Dr. C. Victor Jongeneel and Dr. Christopher J. Fields). In addition, Core will train personnel from each CARE Project in the epigenetic assays utilized in the CARE.

 

dmDr. Dulal Bhaumik Dept. of Psychiatry, UIC is serving as a biostatistician for the CARE.

 

 

 

 

 

 

 

 

 

 

     

                                                                                                                                                                                                       

 

 

Training Opportunities

Capture3CARE will provide resources and a scientifically enriched environment for training opportunities, coordinated by Dr. Mark Rasenick, dept. of Biophysics and Physiology and Psychiatry UIC.

CARE investigators are currently working with several MD/PhD students from MSTP program of UIC, as well as PhD students from Neuroscience Graduate Program of UIC.

http://chicago.medicine.uic.edu/mstp (MSTP)

http://www.uic.edu/depts/neurosci/program.htm  (Neuroscience Graduate Program of UIC.)

 

 

 

 

 

 

 

                                                                                                                                                                                                                                               

Links

 

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