Scientific Publications - Pediatric Brain Research and Intervention Center

Schenkel LS, Wes, AE, Jacobs R, Sweeney JA, Pavuluri MN. Cognitive dysfunction is worse among pediatric patients with bipolar disorder type I than type II. Journal of Child Psychiatry and Psychology. 2012 Jul;53(7):775-81. PMID: 22339488
Coombes SA, Corcos DM, Pavuluri MN, Vaillancourt DE. Maintaining Force Control Despite Changes in Emotional Context Engages Dorsomedial Prefrontal and Premotor Cortex. Cereb Cortex. 2012 March; 22(3): 616–627. PMCID: PMC3278319
Pavuluri MN, Passarotti AM, Fitzgerald JM, Wegbreit E, Sweeney JA. Risperidone and divalproex differentially engage the fronto-striato-temporal circuitry in pediatric mania: a pharmacological functional magnetic resonance imaging study. J Am Acad Child Adolesc Psychiatry. 2012 Feb;51(2):157-170.e5. PMCID: PMC3357915
Pavuluri MN, Ellis JA, Wegbreit E, Passarotti AM, Stevens MC. Pharmacotherapy impacts functional connectivity among affective circuits during response inhibition in pediatric mania. Behavioural Brain Research. 2012 Jan 15;226(2):493-503.
Passrotti A, Ellis J, Wegbreit E, Stevens M, Pavuluri M. Reduced Functional Connectivity of Prefrontal Regions and Amygdala within Affect and Working Memory Networks in Pediatric Bipolar Disorder. Brain Connect. 2012 Oct 4. PMID: 23035965
Nanayakkara S, Pullagurla K, Pavuluri M. Suicidal Behavior in Pediatric Population Neurobiology and the Missing Links in Assessing Risk among Patients with Bipolar Disorder. The Neurobiological Basis of Suicide. Boca Raton, FL: CRC Press; 2012. Chapter 16. PMID: 23035292
Shankman SA, Katz AC, Passarotti AM, Pavuluri MN. Deficits in emotion recognition in pediatric bipolar disorder: The mediating effects of irritability. J Affect Disord. 2012 Sep 7. PMID: 22963899
Lu LH, Zhou XJ, Fitzgerald J, Keedy SK, Reilly JL, Passarotti AM, Sweeney JA, Pavuluri M. Microstructural abnormalities of white matter differentiate pediatric and adult-onset bipolar disorder. Bipolar Disord. 2012 Sep: 14(6):597-606. PMID: 22882719

West A, Celio C, Henry D, Pavuluri MN. Child mania rating scale-parent version: a valid measure of symptom change due to pharmacotherapy. Journal of Affective Disorders. 2011 Jan;128(1-2):112-9. PMCID: PMC2994944
West AE, Weinstein SM, Celio CI, Henry D, Pavuluri MN. Co-morbid Disruptive Behavior Disorder and Aggression Predict Functional Outcomes and Differential Response to Risperidone Versus Divalproex in Pharmacotherapy for Pediatric Bipolar Disorder. J Child Adolesc Psychopharmacol. 2011 Dec;21(6):545-53. PMCID: PMC3243464
Jacobs RH, Pavuluri MN, Schenkel LS, Palmer A, Shah K, Vemuri D, Whited S, Little DM. Negative emotion impacts memory for verbal discourse in pediatric bipolar disorder. Bipolar Disord. 2011 May;13(3):287-93. PMID: 21676131
Pavuluri MN, Passarotti AM, Lu LH, Carbray JA, Sweeney JA. Double-blind randomized trial of risperidone versus divalproex in pediatric bipolar disorder: fMRI outcomes. Psychiatry Research: Neuroimaging. 2011 Jul;193(1):28-37. PMCID: PMC3105215
Findling RL, Kafantaris V, Pavuluri MN , McNamara NK, McClellan J, Frazier JA, Sikich L, Kowatch R, Lingler J, Faber J, Rowles BM, Clemons TE, Taylor-Zapata P. The Collaborative Lithium Trials (CoLT): Dosing strategies for lithium monotherapy in children and adolescents with bipolar I disorder. Journal of Child and Adolescent Psychopharmacology, 2011;21(3): 195-205. PMCID: PMC3111866
Passarotti AM, Sweeney JA, Pavuluri MN. Fronto-limbic dysfunction in mania pre-treatment and persistent amygdala over-activity post treatment in pediatric bipolar disorder. Psychopharmacology. 2011 Aug;216(4):485-99. PMCID: PMC3174733
Mayanil T, Pavuluri MN. A 11 year old boy with ongoing psychotic symptoms. Psychiatric Annals, 2011;41(6): 319-321.
Mayanil T, Wegbreit E, Fitzgerald J, Pavuluri MN. Emerging biosignature of brain function and intervention in pediatric bipolar disorder. Minerva pediatrica, 2011;63(3), 183-200. PMID: 21654599
D'Cruz AM, Ragozzino ME, Mosconi MW, Pavuluri MN, Sweeney JA: Human reversal learning under conditions of certain versus uncertain outcomes. NeuroImage, 56, 2011, 315-322. PMCID: PMC3096874
Passarotti AM, Pavuluri MN. Brain functional domains inform therapeutic interventions in attention-deficit/hyperactivity disorder and pediatric bipolar disorder. Expert Rev Neurother. 2011 June; 11(6): 897–914. PMCID: PMC3129632
West AE, Celio CI, Henry DB, Pavuluri MN. Child Mania Rating Scale-Parent Version: A valid measure of symptom change due to pharmacotherapy. Journal of Affective Disorders. 2011: vol 128; 112-119. PMID: 20858565
Wegbreit E, Ellis JA, Nandam A, Fitzgerald JM, Passarotti AM, Pavuluri MN, Stevens MC. Amygdala functional connectivity predicts pharmacotherapy outcome in pediatric bipolar disorder. Brain Connectivity, 1(5), 411-422. PMID: 22432455

Passarotti AM, Sweeney JA, Pavuluri, MN. Differential Engagement of Cognitive and Affective Neural Systems in Pediatric Bipolar Disorder and Attention Deficit Hyperactivity Disorder. Journal of International Neuroscience Society. J Int Neuropsychol Soc. 2010 Jan: 16(1); 106-17. PMCID: PMC3169194
Passarotti, AM, Sweeney, A., Pavuluri MN. Neural Correlates of Response Inhibition Deficits in Pediatric Bipolar Disorder and Attention Deficit Hyperactivity Disorder. Psychiatry Research: Neuroimaging. Psychiatry Res.2010 Jan 30:181(1); 36-43. PMCID: PMC2795009
Pandey GN, Dwivedi Y, Rizavi HS, Ren X, Zhang H, Pavuluri MN. Brain-Derived Neurotrophic Factor Gene and Protein Expression in Pediatric and Adult Depressed Subjects. Progress in Neuro-Psychopharmacology & Biological Psychiatry, 2010 May;34(4):645-51. PMID: 20227453
Pavuluri MN, Passarotti AM, Mohammed T, Carbray JA, Sweeney JA. Enhanced Working And Verbal Memory After Lamotrigine Treatment in Pediatric Bipolar Disorder. Bipolar Disorders 2010 Mar;12(2):213-20. PMCID: PMC2858356
Pavuluri MN, Passarotti AM, Harral EM, and Sweeney JA. Enhanced Prefrontal Function With Pharmacotherapy on a Response Inhibition Task in Adolescent Bipolar Disorder. Journal of Clinical Psychiatry, 2010 Nov;71(11):1526-34. PMCID: PMC2994986
Findling RL, Landersdorfer CB, Kafantaris V, Pavuluri MN, McNamara NK, McClellan J, Frazier JA, Sikich L, Kowatch R, Lingler J, Faber J, Taylor-Zapata P, Jusko WJ. First-Dose Pharmacokinetics of Lithium Carbonate in Children and Adolescents. Journal of Clinical Psychopharmacology. 2010;30(4): 404-410. PMCID: PMC2967308
Pavuluri MN, Henry DB, Findling RL, Parnes SA, Carbray JA, Mohammed T, Janicak PG, Sweeney JA; Double-Blind Randomized Trial of Risperidone versus Divalproex in Pediatric Bipolar Disorder. Bipolar Disorders, 2010 Sep; 12(6):593-605. PMCID: PMC3013630
Pavuluri MN, Passarotti AM, Parnes SA, Fitzgerald JM, Sweeney JA. A Pharmacological fMRI Study Probing the Interface of Cognitive and Emotional Brain Systems in Pediatric Bipolar Disorder. Journal of Child and Adolescent Psychopharmacology, 2010 Oct; 20(5):395-406. PMCID: PMC2982709
Passarotti, AM, Sweeney JA, Pavuluri, MN (2010). Emotion Processing Influences Working Memory Circuits in Pediatric Bipolar Disorder and Attention Deficit Hyperactivity Disorder. Journal of the American Academy of Child and Adolescent Psychiatry 9 (10), 1064-1080. PMCID: PMC2957818
Pavuluri MN. Effects of early intervention on the course of bipolar disorder: theories and realities. Current Psychiatry Reports. 2010 Dec;12(6):490-8. PMID: 20922506

West AE, Pavuluri MN. Psychosocial Treatments for Childhood and Adolescent Bipolar. Child and Adolescent Psychiatric Clinics of North America 2009: Vol 18(2):471-482. PMID: 19264274
Pavuluri MN, West A, Hill K, Jindal K Sweeney JA. Neurocognitive Function in Pediatric Bipolar Disorder: Three-Year Follow-up Shows Cognitive Development Lagging Behind Healthy Youths. Journal of American Academy of Child and Adolescent Psychiatry 2009: Vol 48(3):299-307. PMCID: PMC2773500
Pavuluri MN, Passarotti A.M., Harral E.M., Sweeney JA. An fMRI Study of the Neural Correlates of Incidental versus Directed Emotion Processing in Pediatric Bipolar Disorder. Journal of American Academy of Child and Adolescent Psychiatry 2009: Vol 48(3): 308-319. PMCID: PMC2772656
Pavuluri MN, Yang S, Kamineni K, Passarotti AM, Srinivasan G, Harral EM, Sweeney JA, Zhou XJ. Diffusion tensor imaging study of white matter fiber tracts in pediatric bipolar disorder and attention deficit hyperactivity disorder. Biological Psychiatry: 2009: Vol 65 (7): 586-593. PMCID: PMC2677389
Pavuluri MN, Henry DB, Moss M, Mohammed T, Carbray JA, Sweeney JA. Effectiveness of lamotrigine in maintaining symptom control in pediatric bipolar disorder. Journal of Child and Adolescent Psychopharmacology 2009: Vol 19(1): 75-82. PMCID: PMC2692234
Pavuluri MN, Leventhal B. Book review of Psychiatry, Third Edition, edited by Allan Tasman, Jerald Kay, Jeffrey A. Lieberman, Michael B. First, and Mario Maj. Hoboken that was published in the American Journal of Psychiatry 166 (7): 835. (2009).
Carlson GA, Findling RL, Post RM, Birmaher B, Blumberg HP, Correll C, DelBello MP, Fristad M, Frazier J, Hammen C, Hinshaw SP, Kowatch R, Leibenluft E, Meyer SE, Pavuluri MN, Wagner KD, Tohen M. AACAP 2006 Research Forum-Advancing research in early-onset bipolar disorder: barriers and suggestions. Journal of Child and Adolescent Psychopharmacology 2009 Vol. 19(1): 3-12. PMID: 19232018
West, A. E., Jacobs, R. H., Westerholm, R., Lee, A., Carbray, J., Heidenreich, J. & Pavuluri, M.N. Child and family-focused cognitive-behavioral therapy for pediatric bipolar disorder: pilot study of group treatment format. Journal of the Canadian Academy of Child and Adolescent Psychiatry, Special Issue: International Perspectives on Pediatric Bipolar Disorder. Aug. 2009. Vol. 18 (3): 239-246. PMCID: PMC2732730
Kraguljac NV, Montori VM, Pavuluri MN, Chai HS, Unal SS. Efficacy of omega-3 fatty acids in mood disorders - a systemic review and met analysis. Psychopharmacology Bulletin. Psychopharmacol Bull. 2009:42(3);39-54. PMID: 19752840
Passarotti AM, Sweeney JA, Pavuluri MN. Neural correlates of incidental and directed facial emotion processing in adolescents and adults. Soc Cogn Affect Neurosci. 2009 Dec;4(4):387-98. PMCID: PMC2799953

Pandey GN, Dwivedi Y, Pavuluri MN. Decreased Protein Kinase C (PKC) in Platelets of Pediatric Bipolar Patients: Effect of Treatment with Mood Stabilizing Drugs. Journal of Psychiatric Research, 2008, 42: 106-116. PMCID: PMC2190755
West AE, Schenkel LS, Pavuluri, MN. Early childhood temperament in pediatric bipolar disorder and attention deficit hyperactivity disorder. Journal of Clinical Psychology, 2008, 64:402-421. PMID: 18324662
Schenkel LS, Patel NB, Harral EM, West AE, Pavuluri MN. Parent-child interactions in pediatric bipolar disorder. Journal of Clinical Psychology. 2008, 64:422-437. PMID: 18357574
Henry DB, Pavuluri MN, Youngstrom E, Birmaher B. Accuracy of brief and full forms of a Mania Rating Scale. Journal of Clinical Psychology. 2008, 64:368-381. PMID: 18302291
Bishop JR and Pavuluri MN. Review of risperidone for the treatment of pediatric and adolescent bipolar disorder and schizophrenia. Neuropsychiatric Disease and Treatment. 2008. 4: 55-68 PMCID: PMC2515898
Bogarapu S, Bishop JR, Krueger C, Pavuluri MN. Complementary medicines in pediatric bipolar disorder. Minerva Pediatrica. 2008: 60(1):103-14. PMID: 18277369
Pavuluri MN, Oconnor-Marlow M, Harral E, Sweeney JA. An fMRI study of the interface between affective and cognitive neural circuitry in pediatric bipolar disorder. Psychiatric Research-Neuroimaging. 2008: 162 (3): 244-255. PMCID: PMC2323905
Schenkel, LS, Marlow-O'Connor M, Moss M, Sweeney JA, Pavuluri MN. Theory of mind and social inference in pediatric bipolar disorder. Psychological Medicine. 2008: 38: 791-800. PMCID: PMC3221606
Hill SK, Harris MSH, Herbener ES, Pavuluri M, Sweeney JA. Neurocognitive allied phenotypes for schizophrenia and bipolar disorder. Schizophrenia Bulletin. 2008: 10.1093: 1-17. PMCID: PMC2632447
Pavuluri MN, Passarotti A. Emotion processing in pediatric bipolar disorder. Expert Review of Neurotherapeutics. 2008:Vol 8:1381-1387
Pavuluri MN, Sweeney JA. Integrating functional brain neuroimaging and developmental cognitive neuroscience in child psychiatry research. Journal of American Academy of Child and Adolescent Psychiatry. 2008: Vol 47(11): 1273-1288 PMCID: PMC2627505
Pandey GN, Rizavi HS, Dwivedi Y, Pavuluri, MN. Brain-derived neurotrophic factor gene expression in pediatric bipolar disorder: effects of treatment and clinical response. Journal of American Academy of Child and Adolescent Psychiatry 2008: Vol47(9):1077-85. PMID: 18664999
Findling RL, Frazier JA, Kafantaris V, Kowatch R, McClellan J, Pavuluri M, Sikich L, Hlastala S, Hooper SR, Demeter CA, Bedoya D, Browstein B, Taylor-Zapata P. The collaborative lithium trials (CoLT): specific aims, methods, and implementation. Child and Adolescent Psychiatry and Mental Health, 2008 2:21: 1-13. PMCID: PMC2531078

West, A.E., Pavuluri, MN. Maintenance model of integrated psychosocial treatment in pediatric bipolar disorder. Journal of the American Academy of Child and Adolescent Psychiatry, 2007, 46 (2), 205-212. PMID: 17242624
Schenkel LS, Pavuluri MN, Herbener ES, Harral EM, and Sweeney JA. Facial emotion processing in acutely ill and euthymic patients with pediatric bipolar disorder. Journal of American Academy of Child and Adolescent Psychiatry, 2007: 46(8):1070-1079. PMID: 17667485
Pavuluri MN, Oconnor-Marlow M, Harral E, Sweeney JA. Role of the affective circuitry during facial emotion processing in pediatric bipolar disorder. Biological Psychiatry, 2007: 62:158-167. PMID: 17097071
Pavuluri, MN, Bishop, JR. Pediatric Bipolar Disorder: Translation of Research Findings to Clinical Practice. Current Medical Literature: Psychiatry, 2007, 18 (1), 1-12.

Pavuluri MN, Schenkel LS, Aryal S, Harral E, S. Hill SK, Herbener ES, Sweeney JA. Neurocognitive function in unmedicated manic and medicated euthymic pediatric bipolar patients. American Journal of Psychiatry, 2006, 163: 286-293. PMID: 16449483
Pavuluri MN, Henry D, Devineni B, Carbray J, Birmaher B. Child mania rating scale: development, reliability and validity. Journal of American Academy of Child and Adolescent Psychiatry, 2006, 45:5550-560. PMID: 16601399
Pavuluri MN, Henry D, Carbray J, Sampson G, Naylor M, Janicak PG. A one-year open-label trial of risperidone augmentation in lithium nonresponder youth withpreschool-onset bipolar disorder. Journal of Child and Adolescent Psychopharmacology, 2006, Vol 16, 3:336-350. PMID: 16768641
Pavuluri MN, Oconnor-Marlow M, Harral E, Moss M, Sweeney JA. Impact of neurocognitive function on academic difficulties in pediatric bipolar disorder: a clinical translation. Biological Psychiatry, 2006, 60 (9): 951-956. PMID:16730333
Pavuluri MN, Henry D, Nadimpalli S, Oconnor-Marlow M, Sweeney JA. Biological risk factors in pediatric bipolar disorder. Biological Psychiatry, 2006, 60 (9): 936-941. PMID: 16806102

Pavuluri MN, Herbener ES, Sweeney JA. Affect regulation: a systems neuroscience perspective. Neuropsychiatr Dis Treat. 2005 Mar;1(1):9-15. PMCID: PMC2426811
Pavuluri MN, Henry D, Naylor M, Carbray J, Janicak PG. Divalproex sodium in pediatric mixed mania: a 6-month prospective trial. Bipolar Disorders, 2005, 7: 266-273. PMID: 15898964
Pavuluri MN, Birmaher B, Naylor M. Pediatric bipolar disorder: a review of the past 10 years. Journal of American Academy of Child and Adolescent Psychiatry, 2005, 44 (9): 846-871. PMID: 16113615
Pavuluri MN, Naylor M. Multimodal integrated treatment for youth with bipolar disorder (MITY-BD): research translation of pharmacotherapy algorithm and psychotherapeutic integration into real life practice. Psychiatric Times, 2005, 22: (6) 24-26.
Kampani S, Pavuluri MN. Integrating pharmacotherapy and psychotherapy for pediatric bipolar disorder: translating science to service. Journal of Indian Association of Child and Adolescent Mental Health, 2005, Vol. 1, No. 2, Special Article.

Pavuluri MN, Herbener ES, Sweeney AJ. Psychotic symptoms in pediatric bipolar disorder. Journal of Affective Disorders, 2004; 80(1):19-28. PMID: 15094254
Pavuluri MN, Grayczyk P, Carbray J, Heidenreich J, Henry D, Miklowitz D. Child- and family-focused cognitive-behavioral therapy for pediatric bipolar disorder: developmentand preliminary results. Journal of American Academy of Child and Adolescent Psychiatry, 2004; 43: 528-537. PMID: 15100559
Pavuluri MN, Birmaher B. A practical guide to using ratings of depression and anxiety in child psychiatric practice. Current Psychiatry Report. 2004; 6 (2) 108-116. PMID: 15038913
Pavuluri MN, Henry D, Naylor M, Carbray J, Sampson G, Janicak PG. A pharmacotherapy algorithm for dtabilization and maintenance of pediatric bipolar disorder. Journal of American Academy of Child and Adolescent Psychiatry, 2004; 43 (7): 859-867. PMID: 15213587
Pavuluri MN, Henry D, Naylor M, Sampson G, Carbray J, Janicak PG. Open-labelprospective trial of risperidone in combination with lithium or divalproex sodium in pediatric mania. Journal of Affective Disorders, 2004: 82 (Suppl 1) 103-11. PMID: 15571784
Pavuluri MN, Herbener EC, Sweeney JA. Affect regulation: a systems neuroscience perspective. Neuropsychiatric Disease and Treatment, 2004: 1(1)9-15. PMID: 18568120

Pavuluri MN, Janicak P, Naylor M, Sweeney J. Early recognition and differentiation of pediatric schizophrenia and bipolar disorder. Annals of Adolescent Psychiatry. 2003;27:117-134
Kraus M, Pavuluri MN, Sweeney, JA. fMRI: clinical applications. Contemporary Psychiatry, 2003;2(2):1-8

Pavuluri MN. American and Australian system: crossing the bridge. Australasian Psychiatry, 2002;10(2):162-165.
Dwivedi S, Pavuluri MN, Heidenreich J, Wright T. Response to fluvoxamine augmentation for obsessive and compulsive symptoms in schizophrenia. Journal of Child and Adolescent Psychopharmacology. 2002;12(1):69-70. PMID: 12014598
Pavuluri MN, Janicak PG, Carbray J. Topiramate plus risperidone for controlling weight gain and symptoms in preschool mania. 2002, Journal of Child and Adolescent Psychopharmacology. 2002;12:271-273. PMID: 12427302
Pavuluri MN, Henry D, Allen K. Childhood anxiety and fear. Discriminant validity in clinician's perspective. European Journal of Child and Adolescent Psychiatry. 2002;11:1-8. PMID: 12541006

Huynh H, Luk SL, Singh R, Pavuluri M, Mathai J. Medium term outcome of children given stimulants for attention deficit hyperactivity disorder. Journal of Child Psychology and Psychiatry. 1999;4:61-67.
Pavuluri MN, Luk SL, McGee R. Parent reported preschool attention deficit hyperactivity: measurement and validity. European Journal of Child and Adolescent Psychiatry. 1999;8:126-133. PMID: 10435461

Pavuluri MN, Luk SL. Recognition and classification of preschool psychopathology: a review. Australian and New Zealand Journal of Psychiatry. 1998;32:642-649. PMID: 9805586

Pavuluri MN, Luk SL, McGee R. Help-seeking for behavior problems by parents of preschool children: a community study. Journal of American Academy of Child and Adolescent Psychiatry. 1996; 35: 215-222. PMID: 8720631
Pavuluri MN, Luk SL. Pattern of preschool behavior problems in New Zealand, Using the Behavior Check List. Journal of Paediatrics and Child Health. 1996;32:132-137. PMID: 8860387
Pavuluri MN, Smith M. Principles and practice of cognitive behaviour therapy in working with parents of young children with behaviour disorder. Australian Journal of Early Childhood. 1996;21(2):22-27.
Pavuluri MN, Smith M, Luk SL. A neuroimmune hypothesis for the aetiopathology of viral illness and manic depression: a case report of an adolescent. Journal of Affective Disorders. 1996;39:7-11. PMID: 8835648
Pavuluri MN, Park S. A community consultation clinic in a paediatric hospital. Australasian Psychiatry, 1996;4:68-70.
Pavuluri MN, Adler R. Depression in children. Journal of Ambulatory Paediatrics 1996.

Pavuluri MN, Luk SL, Clarkson J, McGee R. A community study of preschool behaviour disorder in New Zealand. Australian and New Zealand Journal of Psychiatry. 1995;29:454-462. PMID: 8573049