People: Faculty
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Jeffery R. Bishop, PharmD
Director, Psychiatric Pharmacogenomics
Assistant Professor of Pharmacy Practice and Psychiatry

Dr. Bishop is an investigator in the UIC College of Pharmacy Pharmacogenetics Laboratory. His area of expertise is investigating pharmacogenetic candidate genes as predictors of response and adverse events in persons treated with psychiatric medications. He is currently involved with studies of the pharmacogenetics of risperidone in first episode schizophrenia patients, the pharmacogenetics of agents used in pediatric bipolar disorder, and the pharmacogenetics of adverse effects of SSRIs in person with depression.

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Julie A. Carbray, PhD, APN, PMHCNS-BC
Administrative Director, Pediatric Mood Disorders Program
Clinical Professor

Dr. Carbray holds her PhD (93) and Master of Science (88) degrees from Rush University, Chicago and her Bachelors of Science (87) degree from Purdue University in West Lafayette, Indiana. A Clinical Professor of Psychiatry and Nursing at the University of Illinois at Chicago, she has been on faculty at UIC since 1993. As faculty in Nursing and Psychiatry, Dr. Carbray teaches course content in psychopharmacology, mood disorders, and development and therapeutic interventions with children and adolescents for students from various multidisciplinary programs within the UIC community. Dr. Carbray has also been a liaison with the Chicago Police Department’s Crisis Intervention Team, which trains officers about interacting with children with mental illness. As the Administrative Director of the Pediatric Mood Disorder Clinic, Dr. Carbray manages the clinical programs and multidisciplinary training for the clinic, and is a clinical expert in the area of children and adolescents with mood disorders. As a clinician, Dr. Carbray has a national reputation of excellence in serving families of children with mood disorders, and was recognized by the UIC community in 2008 by receiving the Karen Gousman Excellence in Nursing Award and the American Psychiatric Nurses Association’s (APNA) Best Practices in Outpatient Mental Health Nursing Award.

With a particular focus on helping families to manage their children with mood disorders, Dr. Carbray supervises the parent component of the RAINBOW group therapy program for children with Bipolar Disorder. Dr. Carbray currently is engaged in programs of research that are investigating the psychopharmacology of mood disorders, neurobiology of mood disorders, detecting depressive symptoms in minority youth, and family response to childhood mood disorders.

Dr. Carbray is an internationally recognized speaker and clinical expert on therapeutic work with children and adolescents with mood disorders. In particular, Dr. Carbray has expertise with psychopharmacologic interventions and developmentally based work with children and adolescents. Dr. Carbray is currently involved in research that is testing models of care for children and adolescents with Mood Disorders, psychopharmacologic interventions in mood disorders, and has co-authored scientific papers in this area of expertise. Dr. Carbray is a leader in the field of advanced practice psychiatric nursing, and chairs the APNA Clinical Psychopharmacology Institute and serves on the National Child and Adolescent Practice Council and Illinois APNA Board of Directors.

AFFILIATIONS/MEMBERSHIPS

  • American Psychiatric Nurses Association (APNA)
  • Illinois Advanced Practice Nurses Association
  • Child and Adolescent Bipolar Foundation Professional Member
  • Sigma Theta Tau Member

PROJECTS

  • Collaborative Lithium Trials (COLT)
  • Psychosocial Treatment in Pediatric Bipolar Disorder
  • Affective Neuroscience of Pediatric Bipolar Disorder
  • Developing Brain Function in Adolescent Bipolar Disorder

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Rachel Jacobs, PhD
Research Assistant Professor of Psychiatry

Dr. Jacobs has a background in treatment outcomes for pediatric mood disorders and is interested in studying mechanisms of effective treatment. Recently, Dr. Jacobs has focused on the problem of relapse in adolescent depression and whether mindfulness may protect against the return of depressive symptoms. Dr. Jacobs attended the University of Michigan where she worked with Susan Nolen-Hoeksema, Ph.D. studying rumination. She obtained her Ph.D. from Northwestern University working with Mark Reinecke, Ph.D. on the Treatment for Adolescents with Depression Study (TADS) and completed postdoctoral work with Bradley Peterson, M.D., Myrna Weissman, Ph.D., and Anne Marie Albano, Ph.D. at Columbia University where her primary focus was learning the methodology of fMRI.

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Lisa H. Lu, PhD
Clinical Assistant Professor

Dr. Lisa Lu is interested in normal and abnormal development of language and motor systems, especially as relates to autism spectrum disorders and learning disabilities. Other research interests include using neuroimaging techniques (e.g., fMRI, DTI) to correlate neural systems with behavior, affect regulation in autism, the interface between cognitive processes and affective regulation, Bipolar Disorder, and ADHD.

“If something is worth doing, it’s worth doing well.”

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Sonali Nanayakkara, MD
Medical Director, Pediatric Mood Disorders Program
Assistant Professor of Clinical Psychiatry

Dr. Nanayakkara is a child psychiatrist with expertise in treating children and adolescents with mood disorders. As Medical Director of Pediatric Mood Disorders Clinic, Dr. Nanayakkara directly supervises training of child psychiatry fellows and medical students in the clinic. She also helps to manage treatment in a multidisciplinary setting to address needs of the surrounding underserved population. In addition, she is currently involved with research studies that are investigating the psychopharmacology and neurobiology of mood disorders.

“Be the change that you want to see in the world.” - Mahatma Gandhi

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Alessandra M. Passarotti, PhD
Assistant Professor in Psychiatry

Dr. Passarotti is an Assistant Professor at the UIC Department of Psychiatry, and the Director of the Cognitive Neuroscience lab within the Pediatric BRAIN Center. She uses cognitive paradigms, conventional fMRI and functional connectivity methods to examine the bases of behavior control, and the differential neural mechanisms of affective and cognitive impulsivity in pediatric population such as PBD and ADHD, in order to better person_textrm diagnosis and more targeted intervention. She has received the NARSAD Young Investigator Award, to examine the behavioral and neural bases of reward-related mechanisms as they interact with cognitive and affective systems in pediatric bipolar disorder (PBD) and ADHD, and The Depressive and Bipolar Disorder Alternative Treatment Foundation Award to develop cognitive intervention for affective impulsivity in PBD. Based on these studies, she is currently developing a cognitive intervention program for children with attention and working memory problems. Dr. Passarotti obtained her Ph.D. in Biological Psychology at the University of Illinois at Urbana-Champaign, where she also completed a practicum in developmental clinical neuropsychology. She then specialized in developmental fMRI at the University of California, San Diego.

“The noblest pleasure is the joy of understanding.” – Leonardo da Vinci

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Sally M. Weinstein, PhD
Visiting Research Assistant Professor
Licensed Clinical Psychologist

Dr. Weinstein received a Bachelor of Science from Duke University (2001) and obtained her Ph.D. in Clinical Psychology from the University of Illinois at Chicago (2009). Dr. Weinstein completed her Internship in Child Clinical and Pediatric Psychology at La Rabida Children’s Hospital in Chicago, Illinois (2009), and completed a two-year Postdoctoral Fellowship, funded by the National Institutes of Health, within the Pediatric Mood Disorders Program/Pediatric Brain Research and Intervention Center at the University of Illinois at Chicago (2011). She is currently funded by the American Foundation for Suicide Prevention to examine risk factors and treatment for suicidality among children and adolescents with bipolar disorder.

Dr. Weinstein is currently engaged in programs of research investigating the psychosocial treatment of children with bipolar disorder, and the assessment and treatment of suicidality within pediatric bipolar disorder. Dr. Weinstein also provides clinical evaluations and treatment for children and adolescents with mood disorders, facilitates the RAINBOW Cognitive Behavioral Group Therapy Program for children with bipolar spectrum disorders, and facilitates a cognitive-behavioral group treatment program for adolescent girls with depressive disorders. In addition, she supervises the clinical development of clinical psychology graduate students and interns involved in the Pediatric Mood Disorders Program.

INTERESTS
Child and adolescent mental health; pediatric mood disorders, particularly pediatric bipolar disorder and youth suicidality; cognitive behavioral treatment (CBT) for child and adolescent psychopathology; psychosocial intervention research; developmental psychopathology; risk for development of youth smoking and risky behaviors.

PROJECTS
Identifying Risk Factors and Intervention Methods to Prevent Suicide in Pediatric Bipolar Disorder (PI: Weinstein)
Psychosocial Treatment for Pediatric Bipolar Disorder (PI: West)

Publications

West, A.E., Weinstein, S.M., Celio, C., Henry, D., & Pavuluri, M.N. (2011). Comorbid Disruptive Behavior Disorder and Aggression Predict Functional Outcomes and Differential Response to Risperidone versus Divalproex in Pharmacotherapy for Pediatric Bipolar Disorder. Journal of Child and Adolescent Psychopharmacology,

West, A.E., & Weinstein, S.M. (in press). Pediatric Bipolar Disorder. In R.B. Mennuti, R.W. Christner, & A. Freeman (Eds.) Cognitive-Behavioral Interventions in Educational Settings: A Handbook for Practice (Second Edition). New York: Routledge Publishing.

Weinstein, S.M. & West, A.E. (2009). Cognitive Behavioral Therapy for Pediatric Bipolar Disorder. In: Evidence-Based Mental Health Treatment for Children and Adolescents, http://www.effectivechildtherapy.com/.

Weinstein, S.M., Mermelstein, R., Shiffman, S., and Flay, B. (2008). Mood variability and cigarette smoking escalation among adolescents. Psychology of Addictive Behaviors, 22, 504 – 513.

Weinstein, S.M., & Mermelstein, R.J. (2007). Relations between daily activities and adolescent mood: The role of autonomy. Journal of Clinical Child and Adolescent Psychology, 36, 1 – 13.

Weinstein, S.M., Mermelstein, R.J., Hankin, B.L., Hedeker, D., and Flay, B. (2007). Longitudinal patterns of daily affect and global mood during adolescence. Journal of Research on Adolescence, 17, 587-600.

Weinstein, S.M., Mermelstein, R.J., Hedeker, D., Hankin, B.L., and Flay, B. (2006). The time-varying influences of peer and family support on adolescent daily positive and negative affect. Journal of Clinical Child and Adolescent Psychology, 35, 420 – 430.

Kassel, J.D., Weinstein, S., Skitch, S., Veilleux, J., and Mermelstein, R. (2005). The development of substance abuse in adolescence: Correlates, causes, and consequences. In B.L. Hankin and J.R.Z. Abela (Eds.), Developmental Psychopathology: A vulnerability-stress perspective. Thousand Oaks, CA: Sage Publications.
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Amy West, PhD
Director, Pediatric Intervention Research in Affect Regulation and Mood Disorders (PIRAMD)
Assistant Professor in Psychiatry
Assistant Professor in Clinical Psychology
Licensed Clinical Psychologist

Dr. West is an Assistant Professor in the Department of Psychiatry and also holds an appointment in the Department of Psychology at the University of Illinois at Chicago. Her research broadly focuses on the use of psychosocial interventions in the treatment of pediatric mood disorders. She is currently funded by the National Institutes of Mental Health to study a family-based cognitive-behavioral intervention (child and family-focused cognitive-behavioral therapy, CFF-CBT or the RAINBOW program) for children 7-13 with bipolar disorder. Dr. West also has research interests in the developmental psychopathology of mood disorders in children, treatment mechanisms in psychosocial interventions, suicidal behavior in pediatric bipolar disorder, and developing psychosocial treatments that are culturally-relevant to unique populations. Dr. West received a B.A. in Psychology from Stanford University, her Ph.D. in Clinical Psychology from the University of Virginia, and completed her pre-doctoral internship and post-doctoral fellowship at Harvard Medical School/Children's Hospital Boston.

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Minjie Wu, PhD
Director, Neuroimaging Methods
Research Assistant Professor in Psychiatry

Dr. Wu is a Research Assistant Professor in the Department of Psychiatry of UIC and the Director of Neuroimaging Methods at the UIC Pediatric BRAIN Center. At the BRAIN Center, Dr. Wu is developing advanced functional and structural MR imaging techniques (including T1w, DTI, resting-state and task-evoked fMRI) and applying these techniques to characterize the developmental trajectories of normal brain maturation as well as the developmental perturbations or deviations in neuropsychiatric disorders. These include: map the abnormally engaged resting state affective, executive, and sensorimotor networks in psychotropic naïve patients with pediatric mania using resting state fMRI; probe the affective and cognitive abnormalities in pediatric psychiatric disorders using GLM-based and ICA-based functional connectivity methods on task-evoked fMRI; identify structural abnormalities in major white matter bundles and cortical gray matter in pediatric bipolar disorder.

During her Ph.D. training in Bioengineering at the University of Pittsburgh, Dr. Wu worked at the Geriatric Psychiatry Neuroimaging Lab of the Western Psychiatric Institute and Clinic (WPIC), during which she developed MR imaging algorithms including Automated Labeling Pathway (ALP) for brain image segmentation, automated white matter hyperintensity (WMH) segmentation and localization algorithms, and Optimum MRI Template Selection method for more accurate brain image segmentation/normalization. Using resting-state fMRI, Dr. Wu found altered default-mode network in late-life depression compared to controls. During her curricular practical training in the Section on Tissue Biophysics & Biomimetics (STBB), National Institute of Child Health & Human Development (NICHD)/National Institutes of Health (NIH), Dr. Wu developed the image-registration based EPI distortion correction algorithm for DTI data processing, which is included in the NIH diffusion MRI data processing software package: TORTOISE. During her post-doctoral training at the Department of Neurology, Northwestern University, Dr. Wu used high resolution DTI and resting state connectivity analysis method to study Parkinson's disease.

INTERESTS:
Resting state fMRI, diffusion tensor imaging, task-based fMRI, multi-modality imaging fusion, graph theory, machine learning, normal brain development, pediatric bipolar disorder, late-life depression.

AFFILIATIONS/MEMBERSHIPS
International Society for Magnetic Resonance in Medicine
Organization for Human Brain Mapping

About


The Brain Center and the clinic is a part of the Pediatric Mood Disorders Program, The Colbeth Child and Adolescent Psychiatry Clinic, the Institute for Juvenile Research, and the Department of Psychiatry at the University of Illinois at Chicago.

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1747 West Roosevelt Road
Suite 155, M/C 747
Chicago, IL 60608
Phone: (312) 996-7723
Fax: (312) 413-0063

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