People: Collaborating Faculty
Picture
Yogesh Dwivedi, PhD
Professor of Psychiatry and Pharmacology

Dr. Dwivedi studies molecular neurobiology of mood disorders and suicide. The major focus of his research is to elucidate the molecular and cellular mechanisms associated with mood disorders, stress, and suicidal behavior by integrating basic and clinical neuroscience to comprehensively examine the roles of neurotrophins, cellular signaling, apoptosis, synaptic and structural plasticity. Utilizing various investigative approaches, namely, human postmortem brain, peripheral blood cells, and pre-clinical animal models, Dr. Dwivedi successfully integrated basic and clinical neuroscience. More recently, utilizing microRNA, epigenetic and gene knockout approaches, his group is attempting to unravel the molecular mechanisms that may be responsible for gene regulation in mood disorder and suicide brains.

Picture
David B. Henry, PhD
Professor of Health Policy and Administration

Dr. Henry studies contextual processes that influence individual behavior, child and adolescent development and psychopathology, and prevention. He has published over 50 articles and book chapters in these and other areas. He has been the co-investigator or principal investigator on grants funded by private foundations, the National Institutes of Health, and the Centers for Disease Control and Prevention.

Picture
Chunyu Liu, PhD
Visiting Associate Professor of Psychiatry

Dr. Liu has a long-term interest in understanding of molecular basis of psychiatric diseases. His laboratory participated one of the bipolar genetics research consortiums and discovered the rare copy number variant (CNV) burden in early-onset bipolar disorder. His lab is one of the leading research groups on genome-wide study of postmortem brain gene expression and DNA methylation. He established the methylation quantitative trait loci (mQTLs) in human brain, indicating that DNA methylation of some sequences could be highly regulated by genetic variants. His research has been supported by NIMH, NARSAD, and Brain Research Foundation. He has published more than 50 peer-reviewed papers and several book chapters. Dr. Liu’s major research focuses on using a comprehensive approach that is composed of genetics, bioinformatics, genomics, and animal models to identify the molecular mechanisms of major psychiatric diseases, particularly bipolar disorder and schizophrenia.

Picture
Ghanshyam N. Pandey, PhD
Director, Mood Disorders and Suicide Research
Professor of Pharmacology and Psychiatry

Dr. Pandey is Professor of Pharmacology in the Department of Psychiatry since 1981 and is Director of Biological Research Laboratories. His main research interests are the neurobiology of mood disorders, schizophrenia and suicide. Dr. Pandey is a nationally and internationally renowned expert on biochemical abnormalities associated with mood disorders and suicide. He has been particularly interested in examining the role of serotonergic mechanisms and for that purpose; he has studied primarily the serotonin receptor subtypes (e.g., serotonin2A, serotonin2B and serotonin2C receptors) in various areas of the postmortem brain of suicide victims and normal control subjects.

Phosphoinositide Signaling Pathway

Picture
Michael E. Ragozzino, PhD
Professor of Biological Sciences and Psychology

Dr. Ragozzino investigates the neurobiology of learning and memory related to neurological and psychiatric disorders. The major focus of his research is to elucidate the neurochemical mechanisms that underlie cognitive flexibility and the associated pathophysiology in various brain disorders associated with behavioral inflexibility. His research program integrates basic and clinical neuroscience by developing behavioral tests that can be applied to both preclinical and clinical research. In trying to understanding the neurochemical mechanisms that support cognitive flexibility, Dr. Ragozzino employs different in vivo neurochemical techniques and pharmacological approaches. The goal is to apply novel and effective treatments for a range of disorders marked by cognitive deficits.

Picture
Michael C. Stevens, PhD
Director, Clinical Neuroscience and Development Laboratory
Director, Child and Adolescent Research
Associate Professor of Psychiatry at Yale University
http://www.nrc-iol.org/onrc_labs_cnd.asp

Dr. Stevens directs two complementary programs of research. He leads the Clinical Neuroscience and Development Laboratory, which uses neuroscience research techniques to understand the neurobiological substrates of psychiatric illnesses that develop in childhood and adolescence. He also is the director of Child and Adolescent Research for The Institute of Living at Hartford Hospital. In this role, Dr. Michael C. Stevens is responsible for overseeing and contributing to all pediatric psychiatric research at the Institute.

Picture
Ezra Wegbreit, PhD
Research Fellow at Harvard Medical School
 
Picture
Xiaohong Joe Zhou, PhD, DABR
Director, 3T MR Research Program
Director, MR Physics
Chief Medical Physicist
Professor of Radiology, Neurosurgery, and Bioengineering

The research in in Dr. Zhou’s group is focused primarily on developing diffusion imaging techniques to improve cancer diagnosis, guide surgery, and monitor treatment efficacy. They are particularly interested in developing non-EPI-based data acquisition techniques to achieve high spatial resolution. With the high resolution capability, we are presently exploring a number of applications, including tracking tumor cell infiltration along the white-matter fiber tracts, early detection of tumor recurrent sites, and probing tissue cellularity change during radiation therapy. His group is also interested in selective phosphorus imaging at ultra-high field. We are presently developing efficient RF pulses for 31P selective excitation, and will use the technique to map the 3D distribution of important metabolites, such as phosphorus creatine at 9.4T. The ultimate goal of this project is to develop a robust metabolic imaging marker for human applications.

Picture
Moon-Soo, Lee, M.D., Ph.D
Guest scholar in Pediatric Brain Research and Intervention Center at Department of Psychiatry at the University of Illinois at Chicago

Dr. Lee is an associate Professor in the college of medicine, Korea University. He is also a head of the division of the child and adolescent psychiatry in the department of psychiatry. He is interested in the neuroimaging studies of the pediatric mood disorder patients using diffusion tensor images. He has published more than 70 peer-reviewed papers and several book and textbook chapters. He also has worked as a working staff for the committee of psychiatrists to end school violence in Korea

About


The Brain Center and the clinic is a part of the Pediatric Mood Disorders Program, The Colbeth Child and Adolescent Psychiatry Clinic, the Institute for Juvenile Research, and the Department of Psychiatry at the University of Illinois at Chicago.

Contact


1747 West Roosevelt Road
Suite 155, M/C 747
Chicago, IL 60608
Phone: (312) 996-7723
Fax: (312) 413-0063

Support


Click here to learn more about how your contribution can support and improve the lives of children and adolescents with mental health issues