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Since its early beginnings in the 1890s, our Department has an esteemed history of providing outstanding service

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Before there was a UIC College of Medicine, there was the College of Physicians and Surgeons, known colloquially as

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Learn about the institutes of Department of Psychiatry

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EXCELLENCE EVERYWHERE — in research, education and clinical work

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Rachel H. Jacobs


University of Illinois at Chicago
1747 W. Roosevelt Road, Room 160
Chicago, Illinois 60608

Office Phone:312-413-9178

E-mail: This email address is being protected from spambots. You need JavaScript enabled to view it.


Peters, A.T., Burkhouse, K. Feldhaus, C.G., Langenecker, S.A., & Jacobs, R.H.  (2016). Aberrant resting-state functional connectivity in limbic and cognitive control networks relates to depression, rumination, and mindfulness: A pilot study among adolescents with a history of depression. Journal of Affective Disorders, 200, 178-181.

Jenkins, L.M., Kassel, M.T., Gabriel, L.B., Gowins, J.R., Hymen, E.A., Verges, A., Calamia, M., Crane, N.A., Jacobs, R.H., Ajilore, O., Welsh, R.C., Drevets, W.C., Phillips, M.L., Zubieta, J-K. & Langenecker, S.A. (in press). Amygdala and dorsomedial hyperactivity to emotional faces in youth with remitted Major Depression. Social Cognitive and Affective Neuroscience.

Jacobs, R.H., Barba, A., Gowins, J.R., Klumpp, H., Jenkins, L., Mickey, B.J., Ajilore O., Pecina, M., Sikora, M., Ryan, K.A., Hsu, D.T., Welsh, R.C., Zubieta, J.K., Phan, K.L., & Langenecker, S.A. (2016). Decoupling of the amygdala to other salience network regions in adolescent onset recurrent major depressive disorder. Psychological Medicine

Langenecker, S.A., Jacobs, R.H., Passarotti, A.M. 2014. Current Neural and Behavioral Dimensional Constructs across Mood Disorders. Current Behavioral Neuroscience Reports. Current Behavioral Neuroscience Reports. 1, 144-153.

Curry, J., Silva, S., Rohde, P., Ginsburg, G., Kratochvil, C., Simons, A., Kirchner, J., May, D., Kennard, B., Mayes, T., Feeny, N., Albano, A., Lavanier, S., Reinecke, M., Jacobs, R. , Becker-Weidman, E., Weller, E., Emslie, G., Walkup, J., Kastelic, E., Burns, B., Wells, K., & March, J. (2011). Recovery and recurrence following treatment for adolescent major depression. Archives of General Psychiatry, 68, 263-269.

Jacobs, R.H. , Pine, D.S., Schoeny, M.E., Henry, D.B., Gollan, J.K., Moy, G., Cook, E.H., & Wakschlag, L.S. (2011). Maternal depressive history, teen 5HTTLPR genotype, and the processing of emotional faces: Exploring mechanisms of risk. Behavior Research and Therapy, 49, 80-84.

Jacobs, R.H. , Pavuluri, M.N., Palmer, A., & Little, D.M. (2011). Memory for language discourse in pediatric bipolar disorder: Effects of emotion. Bipolar Disorders, 13, 287-293.

Jacobs, R.H. , Becker-Weidman, E.G., Reinecke, M.A., Jordan, N., Rohde, P., Silva, S.G., & March, J.S. (2010). Treating depressed and oppositional adolescents. Journal of Clinical Child and Adolescent Psychology, 39, 559-567.

Jacobs, R.H. , Reinecke, M.A., Gollan, J.K., Jordan, N., Silva, S.G., & March, J.S. (2010). Extreme thinking in clinically depressed adolescents: Results from the Treatment for Adolescents with Depression Study (TADS). Behavior Research and Therapy, 48, 1155-1159.

Jacobs, R.H. , Silva, S.G., Reinecke, M.A., Curry, J., Kratchovil, C.J., Ginsburg, G., & March, J.S. (2009). DAS perfectionism: A predictor and partial mediator of acute treatment outcome among clinically depressed adolescents. Journal of Clinical Child and Adolescent Psychology, 38,803-813.
TADS Team. (2009). The Treatment for Adolescents with Depression Study (TADS): Outcomes over one year of naturalistic follow-up. American Journal of Psychiatry, 166, 1141-1149.

Jacobs, R.H. , Klein, J.B., Reinecke, M.A., Silva, S.G., Breland-Noble, A., Tonev, S., Martinovich, Z., Rezac, A., Kratochvil, C.J., Jones, J., & March, J.S. (2008). Ethnic differences in attributions and treatment expectancies for adolescent depression. International Journal of Cognitive Therapy, 1, 163-178.

Jacobs, R.H. , Reinecke, M.A., Gollan, J.K., & Kane, P.P. (2008). Empirical evidence of cognitive vulnerability among children and adolescents: A cognitive science and developmental perspective. Clinical Psychology Review, 28, 759-782.
TADS Team. (2007). The Treatment for Adolescents with Depression Study (TADS): Long-term effectiveness and safety outcomes. Archives of General Psychiatry, 64, 1132-1143.  

Curry, J., Silva, S., Rohde, P., Ginsburg, G., Kratochvil, C., Simons, A., Kirchner, J., May, D., Kennard, B., Mayes, T., Feeny, N., Albano, A., Lavanier, S., Reinecke, M., Jacobs, R., Becker-Weidman, E., Weller, E., Emslie, G., Walkup, J., Kastelic, E., Burns, B., Wells, K., & March, J. (2012). Onset of alcohol or substance use disorders following treatment for adolescent depression. Journal of Consulting and Clinical Psychology, 80, 299-312.

Schenkel, L.S., West, A.E., Jacobs, R.H., Sweeney, J.A., & Pavuluri, M.N. (2012). Cognitive dysfunction is worse among pediatric patients with bipolar disorder type I than type II. Journal of Child Psychiatry and Psychology, 53, 775-781.

Rachel H. Jacobs, Ph.D.

Research Assistant Professor
Licensed Clinical Psychologist

Dr. Jacobs has a background in treatment outcomes for pediatric mood disorders and is interested in studying mechanisms of effective treatment. Recently, Dr. Jacobs has focused on the problem of relapse in adolescent depression and whether mindfulness may protect against the return of depressive symptoms. She has received funding from the Klingenstein Third Generation Foundation and UIC Campus Research Board to fund a pilot project in this area.

Dr. Jacobs received her B.A. from the University of Michigan and her Ph.D. from Northwestern University where she was funded by a F31 NRSA to study cognitive change in the treatment of adolescent depression. Her internship in clinical child psychology was completed at IJR. Dr. Jacobs completed a T32 postdoctoral fellowship at Columbia University where her primary focus was learning the methodology of fMRI.


  • Association for Behavioral and Cognitive Therapies


  • CBT for mood and anxiety disorders in children, the use of mindfulness and meditation to prevent relapse of mood disorders, mindful parenting, neuroimaging of treatment outcomes


  • Mindfulness Intervention to study the Neurobiology of Depression (MIND)



  1. Ambulatory Clinic:
    Neuropsychiatric Insitute
    912 S. Wood Steet, Chicago, IL 60612
  2. UIC Hospital
    1740 W Taylor St, Chicago, IL 60612
  3. Institute for Juvenile Research
    1747 W. Roosevelt Rd, Chicago, IL 60608
  4. Psychiatric Institute
    1601 W. Taylor St.Chicago, IL 60612

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