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Pauline Maki

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CONTACT INFORMATION

University of Illinois at Chicago
Department of Psychiatry
Neuropsychiatry Institute
912 W. Wood Street, Room-328
Chicago, IL 60612

Office Phone: (312) 996-6941
E-mail: This email address is being protected from spambots. You need JavaScript enabled to view it.

Assistant: 
Jessica Oakley, 312-996-1647,
This email address is being protected from spambots. You need JavaScript enabled to view it.

 

Chicago Developmental Center for AIDS Research
http://www.chicagocfar.org/

Women’s Interagency HIV Study
http://statepiaps.jhsph.edu/wihs/

KEY PUBLICATIONS

1: Weber MT, Maki PM, McDermott MP. Cognition and mood in perimenopause: A systematic review and meta-analysis. J Steroid Biochem Mol Biol. 2013 Jun 13. doi:pii: S0960-0760(13)00111-8. 10.1016/j.jsbmb.2013.06.001. [Epub ahead of print] PubMed PMID: 23770320.

2: Maki PM. Critical window hypothesis of hormone therapy and cognition: a scientific update on clinical studies. Menopause. 2013 Jun;20(6):695-709. doi:10.1097/GME.0b013e3182960cf8. PubMed PMID: 23715379.

3: Drogos LL, Rubin LH, Geller SE, Banuvar S, Shulman LP, Maki PM. Objective cognitive performance is related to subjective memory complaints in midlife women with moderate to severe vasomotor symptoms. Menopause. 2013 May 13. [Epub ahead of print] PubMed PMID: 23676633.

4: Weber MT, Rubin LH, Maki PM. Cognition in perimenopause: the effect of transition stage. Menopause. 2013 May;20(5):511- 7. doi: 10.1097/GME.0b013e31827655e5. PubMed PMID: 23615642.

5: J Meyer V, Rubin LH, Martin E, Weber KM, Cohen MH, Golub ET, Valcour V, Young MA, Crystal H, Anastos K, Aouizerat BE, Milam J, Maki PM. HIV and recent illicit drug use interact to affect verbal memory in women. J Acquir Immune Defic Syndr. 2013 May 1;63(1):67-76. doi: 10.1097/QAI.0b013e318289565c. PubMed PMID: 23392462;PubMed Central PMCID: PMC3628722.

6: Weber MT, Rubin LH, Maki PM. Cognition in perimenopause: the effect of transition stage. Menopause. 2013 Jan 2. [Epub ahead of print] PubMed PMID:23287890; PubMed Central PMCID: PMC3620712.

7: Maki PM, Rubin LH, Cohen M, Golub ET, Greenblatt RM, Young M, Schwartz RM, Anastos K, Cook JA. Depressive symptoms are increased in the early perimenopausal stage in ethnically diverse human immunodeficiency virus-infected and humanimmunodeficiency virus-uninfected women. Menopause. 2012 Nov;19(11):1215-23. doi: 10.1097/gme.0b013e318255434d. PubMed PMID: 22872013; PubMed Central PMCID: PMC3483358.

8: Maki PM. Minireview: effects of different HT formulations on cognition. Endocrinology. 2012 Aug;153(8):3564-70. doi: 10.1210/en.2012-1175. Epub 2012 Jun 6. Review. PubMed PMID: 22673228.

9: Weber MT, Mapstone M, Staskiewicz J, Maki PM. Reconciling subjective memory complaints with objective memory performance in the menopausal transition.Menopause. 2012 Jul;19(7):735-41. doi: 10.1097/gme.0b013e318241fd22. PubMed PMID:22415562.

10: North American Menopause Society (Maki PM). The 2012 hormone therapy position statement of: The North American Menopause Society. Menopause. 2012 Mar;19(3):257-71. doi: 10.1097/gme.0b013e31824b970a. PubMed PMID: 22367731; PubMed Central PMCID:PMC3443956.

11: Harlow SD, Gass M, Hall JE, Lobo R, Maki P, Rebar RW, Sherman S, Sluss PM, de Villiers TJ; STRAW 10 Collaborative Group. Executive summary of the Stages of Reproductive Aging Workshop + 10: addressing the unfinished agenda of staging reproductive aging. Menopause. 2012 Apr;19(4):387-95. doi:10.1097/gme.0b013e31824d8f40. PubMed PMID: 22343510; PubMed Central PMCID:PMC3340903.

12: Domino SE, Bodurtha J, Nagel JD; BIRCWH Program Leadership (Maki PM). Interdisciplinary research career development: building interdisciplinary research careers in women's health program best practices. J Womens Health (Larchmt). 2011 Nov;20(11):1587-601. doi: 10.1089/jwh.2011.3165. Epub 2011 Sep 16. PubMed PMID:21923414; PubMed Central PMCID: PMC3216063

13: Rubin LH, Cook JA, Grey DD, Weber K, Wells C, Golub ET, Wright RL, Schwartz RM, Goparaju L, Cohan D, Wilson ML, Maki PM. Perinatal depressive symptoms in HIV-infected versus HIV-uninfected women: a prospective study from preconception to postpartum. J Womens Health (Larchmt). 2011 Sep;20(9):1287-95. doi:10.1089/jwh.2010.2485. Epub 2011 Jul 6. PubMed PMID: 21732738; PubMed Central PMCID: PMC3168970.

14: Maki PM, Dennerstein L, Clark M, Guthrie J, LaMontagne P, Fornelli D, Little D, Henderson VW, Resnick SM. Perimenopausal use of hormone therapy is associated with enhanced memory and hippocampal function later in life. Brain Res. 2011 Mar 16;1379:232-43. doi: 10.1016/j.brainres.2010.11.030. Epub 2010 Nov 13. PubMed PMID: 21078303; PubMed Central PMCID: PMC3046212.

 

Pauline Maki, PhD

Professor of Psychiatry and Psychology
Director of Women’s Mental Health Research

Dr. Pauline M. Maki is a Professor in the Departments of Psychiatry and Psychology at the University of Illinois at Chicago. Dr. Maki’s research over the last 12 years has focused on women’s mental and cognitive health. She has a longstanding interest in the effects of sex hormones and phytoestrogens on cognition, brain function, and psychological wellbeing in young, midlife and elderly women. Her brain imaging research led to novel insights into the neural targets of hormone therapy in postmenopausal women.

Dr. Maki received her Ph.D. in experimental psychology from the University of Minnesota in 1994. She received post-graduate training at the Johns Hopkins University School of Medicine in the dementias of aging and at the National Institute on Aging in neuroimaging. In 1999, she joined the Intramural Research Program of the National Institute on Aging, where she became a co-developer and Co-Principal Investigator in the Women’s Health Initiative Study of Cognitive Aging (WHISCA) and Cognition in the Study of Tamoxifen and Raloxifene (Co-STAR).

In 2002, she joined the faculty at the University of Illinois at Chicago, where she received funding from the National Institutes of Health to conduct randomized clinical trials comparing hormone therapy to alternative botanical therapies. Dr. Maki is a member of the North American Menopause Society (NAMS) Board of Trustees, the Chair Elect of the NAMS Research Affairs Committee, and the Director the NAMS Mentorship Program. She has numerous publications on hormones and cognitive function, won a number of NIH awards for her research and service, serves on executive committees for several women’s health advisory boards, and is a frequent international and national speaker on women’s cognitive health. 

Dr. Maki serves as the Chair of the Neurocognitive Working Group of the Women’s Interagency HIV Study (WIHS). The WIHS is the largest longitudinal study of the natural and treated history of HIV in women. In this role she directs the largest study of neurocognition in women with HIV to date; approximately 1,000 HIV-infected women and 600 controls participate in that longitudinal neurocognitive study. Dr. Maki’s particular scientific interests are in the role of genetics and sex-specific risk factors for cognitive impairment, including menopause and sex steroid hormones. She is the PI on two NIH-funded neuroimaging studies examining the impact of HIV and drug use on verbal memory and related neural systems. In other HIV-related service activities, she serves on the Executive Committee Member and Leader of HIV and Aging Emphasis Group, Chicago Developmental Center for AIDS Research.

Interests:
Effects of sex hormones and phytoestrogens on cognition, brain function, and psychological wellbeing in young, midlife and elderly women. Neurocognition in Women with HIV

Affiliations/Memberships:
BIRCWH (Building Interdisciplinary Research Careers in Women’s Health) Advisory Board
North American Menopause Society - Board of Trustees Member
North American Menopause Society - Chair-Elect Research Affairs Committee
North American Menopause Society - Mentorship Program, Director
North American Menopause Society - Mentorship Program, Mentor
Women’s Interagency HIV Study - Head of Neurocognitive Working Group
Chicago Center for AIDS Research - Special Emphasis Area Leader in HIV and Aging
Faculty of 1000 Medicine, Member
Editorial Board Menopause, Member 
 

Projects:
Research Investigation of Soy and Estrogen; Women’s Interagency HIV Study

Directions

Address:

  1. Ambulatory Clinic:
    Neuropsychiatric Insitute
    912 S. Wood Steet, Chicago, IL 60612
  2. UIC Hospital
    1740 W Taylor St, Chicago, IL 60612
  3. Institute for Juvenile Research
    1747 W. Roosevelt Rd, Chicago, IL 60608
  4. Psychiatric Institute
    1601 W. Taylor St.Chicago, IL 60612

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